Inpp4b is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis.

Ann N Y Acad Sci

Clinical Research Institute of Montreal, Départment de Médecine, Université de Montréal, Department of Medicine, McGill University, Montréal, Québec, Canada.

Published: March 2013

Inositol polyphosphate 4-phosphatase type II (Inpp4b) is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis. This short overview summarizes some of the cellular, molecular, and crosstalk signaling mechanisms that control osteoclast and osteoblast differentiation and activation.

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Source
http://dx.doi.org/10.1111/nyas.12014DOI Listing

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