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Screening a transposon-mutagenized soybean population led to the discovery of a recessively inherited chlorotic phenotype. This "y24" phenotype results in smaller stature, weaker stems, and a smaller root system. Genome sequencing identified 15 candidate genes with mutations likely to result in a loss of function.
View Article and Find Full Text PDFAdministration of Burns First Aid Treatment to Aboriginal and Torres Strait Islander children in community settings.
Burns
December 2024
The George Institute for Global Health, UNSW, Sydney, Australia; School of Population Health, UNSW, Sydney, Australia; College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Objective: This paper investigates Burn First Aid Treatment (BFAT) provided to Aboriginal and Torres Strait Islander children in Australia at the scene of injury using data from a population-based cohort study.
Study Design: The participants were 208 Aboriginal and Torres Strait Islander children aged < 16 years who sustained a burns injury between 2015-2018, and their carers. The primary outcome measure was gold standard BFAT, (defined as at least 20 min of cool, running water within 3 h of the injury); additional measures included type of first aid, length of first aid provided, and carer's knowledge of first aid.
High thermal buffer and radiative cooling sodium alginate-based Janus aerogel enables multi-scenario thermal management for firefighting clothing.
Int J Biol Macromol
August 2024
National Local Joint Laboratory for Advanced Textile Processing and Clean Production, Wuhan Textile University, Wuhan 430200, China. Electronic address:
Firefighting clothing is an indispensable protective equipment for firefighters performing rescue activities under extreme heat and fire conditions. However, few bio-based thermal management materials that provide thermal comfort to firefighters in different operational scenarios have been reported. Herein, we present a novel strategy to prepare Janus-type aerogels based on sodium alginate biological macromolecules, consisting of a SiO nanoparticle layer and a microencapsulated paraffin@SiO phase-change composite layer.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to create a new prognostic model to estimate the risk of pulmonary complications after elective surgery, which is the leading cause of post-surgery death.
- Data from a large international cohort of over 86,000 patients was used, applying machine learning techniques to identify risk factors for complications like pneumonia and respiratory distress.
- The model, named the GSU-Pulmonary Score, was validated with additional cohorts and is available as an online tool to assist in patient care and resource management, especially important during pandemic recovery.
Experimental evidence for Parthanatos-like mode of cell death of heat-damaged human skin fibroblasts in a cell culture-based in vitro burn model.
Burns
August 2024
Department for Orthopedics and Trauma Surgery, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Germany.
Article Synopsis
- The study investigates the cellular mechanisms behind heat-induced cell death in human fibroblasts, focusing on how extreme temperatures affect these cells over time.
- Researchers found that heating fibroblasts caused about 50% cell death, with a delayed response that peaked around five hours post-exposure, challenging the idea of traditional caspase-mediated apoptosis.
- Instead, the findings suggest a different death mechanism resembling Parthanatos, characterized by increased PARP1 protein levels and translocation of specific factors into the nucleus, indicating a unique response to heat stress rather than typical apoptotic processes.
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