AI Article Synopsis

  • The study aimed to assess carotid intima-medial thickness (CIMT) and its risk factors among type 2 diabetic, pre-diabetic, and non-diabetic patients experiencing acute strokes.
  • CIMT measurements showed that diabetic and pre-diabetic patients had higher CIMT in the right carotid artery than non-diabetic patients, but results were similar for left carotid measurements across groups.
  • Insulin resistance was notably high in diabetic patients, with age and body mass index showing positive correlations to CIMT, particularly in diabetics, indicating the variability of risk factors impacting CIMT across different glycemic statuses.

Article Abstract

Objective: Measure carotid intima-medial thickness (CIMT), its variability, risk factors, their correlation, in type 2 diabetic (DM), pre-diabetic (PDM) and non-diabetic (NDM) acute strokes.

Methods: Twenty four DM and a matched population of 14 patients each of PDM and NDM strokes were studied. Each group was compared as whole and by gender and stroke segregation. Study parameters were right and left CIMTs (CIMTR, CIMTL), insulin resistance (IR), age, BMI and lipids, correlations between CIMTs and CIMTs with risk markers.

Results: CIMTR was higher in DM and PDM compared to NDM, but CIMTLs did not differ. CIMTs were similar in genders and stroke types of each group. The IR was significantly high only in DM. Age and BMI correlations were predominantly positive and lipids variable except in PDM. Age and IR had better impacts on CIMTs in DM while BMI was poor. Females and infarcts had a more congruous CIMT increment in DM and PDM but male and haemorrhage in NDM.

Conclusion: With similar levels of risk markers, their impacts on the CIMTs are highly variable at various levels of glycaemia. CIMTs were similar in the genders and stroke types of each group, irrespective of the glycemic status. The pre-diabetes group had distinct features.

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