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Toward Equitable Access to Psychosocial Screening in Canada: Validation of the French-Canadian Psychosocial Assessment Tool.
Pediatr Blood Cancer
March 2025
Azrieli Research Centre, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada.
Objective: The Psychosocial Assessment Tool (PAT) is a brief caregiver report, family-centered, psychosocial risk screening tool widely used in pediatrics and available in many languages. Although French is an official language of Canada, a French-Canadian version of the PAT has not yet been validated, which impedes access to this tool for family psychosocial screening. This study aimed to translate, adapt as necessary, and validate the French-Canadian version of the PAT.
View Article and Find Full Text PDFSample Size Adjustment in Sequential Multiple Assignment Randomized Trials.
Stat Med
February 2025
Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY.
Clinical trials are often designed based on limited information about effect sizes and precision parameters with risks of underpowered studies. This is more problematic for SMARTs where strategy effects are based on sequences of treatments. Sample size adjustment offers flexibility through re-estimating sample size during the trial to ensure adequate power at the final analysis.
View Article and Find Full Text PDFHigh-Sensitivity Fluorescent Sensing Platform for Rapid and Selective Detection of Chlorpyrifos Pesticide in Water Samples Using Terbium-Isatin-3-allyl Complex.
J Fluoresc
January 2025
Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
The detection of organophosphorus pesticides, particularly chlorpyrifos, in environmental samples is essential due to their widespread use and associated health risks. In this study, we developed a high-sensitivity fluorescent sensing platform utilizing an Isatin-3-allyl-terbium (IS-Tb) complex in solution for the rapid and selective detection of chlorpyrifos in various water samples. The proposed chemical structure of the complex in solution was evaluated using molar ratio method.
View Article and Find Full Text PDFMethod for extracting elemental sulfur in environmental water and its application to blue tide samples from Tokyo Bay, Japan.
Anal Sci
January 2025
Estuary Research Center, Shimane University, 1060 Nishikawatsu, Matsue, Shimane, 690-8504, Japan.
A simple method for determining elemental sulfur in environmental water was developed and applied to seawater samples collected immediately after the occurrence of blue tides in Tokyo Bay. To investigate the concentration and extraction methods, artificial elemental sulfur was quantitatively produced by oxidizing a sulfide solution with an iodine solution, then used as a standard reagent in the experiments. To concentrate the elemental sulfur in the water sample, glass filter paper (GF/F) was used to filter and collect the elemental sulfur.
View Article and Find Full Text PDFAbsolute quantification of amine metabolites in human cerebrospinal fluid via MS1-centric isotopic N,N-dimethyl leucine (iDiLeu) labeling.
Anal Bioanal Chem
January 2025
Department of Chemistry, University of Wisconsin, Madison, WI, USA.
Quantitative measurement of metabolites is essential to understand biological and disease processes. Absolute quantification by spiking heavy isotope-labeled internal standards and analyzing on mass spectrometry (MS) platform is a key method to determine the concentration of metabolites in biological samples. However, MS-based absolute quantification is often challenged by the commercial availability and high costs of isotope-labeled internal standards.
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