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| http://dx.doi.org/10.1093/pch/17.4.179 | DOI Listing |
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International consensus on research priorities in hypospadias using a Delphi study approach.
J Pediatr Urol
December 2024
Department of Public Health, College of Health Sciences, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar.
Introduction: Hypospadias is a common congenital anomaly of the male genitalia that poses significant management and treatment challenges. Gaining a comprehensive understanding of priority research questions in hypospadiology will be essential to reach agreement on the optimal approach to assessment, treatment, and outcome prediction for affected patients.
Methods: We employed a consensus-building Delphi method to identify and prioritize research questions in the hypospadias field.
Core-shell vector-mediated co-delivery of CRISPR/Cas9 system and hydrophobic drugs against triple-negative breast cancer stem cells.
J Control Release
December 2024
Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, DuShuHu High Education Zone, Suzhou, Jiangsu Province 215123, China. Electronic address:
Cancer stem cells (CSCs) play an important role in the development of triple-negative breast cancer (TNBC), including metastasis, invasion, tumorigenicity, and drug resistance. Moreover, non-CSCs can spontaneously transform into CSCs in special tumor microenvironments, thereby leading to poor prognosis or even failed treatments. Therefore, reversing tumor stem cells into normal tumor cells in a sustained-acting manner is a promising strategy.
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Sci Rep
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Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
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View Article and Find Full Text PDFExploring UK clinician perceptions of through-knee amputation compared to above-knee amputation: a mixed methods study.
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Institute for Clinical and Applied Health Research, Hull York Medical School, University of Hull, Hull, United Kingdom.
Background: Through-knee amputation (TKA) has potential advantages over above-knee amputation (AKA) but is rarely performed in the United Kingdom (UK). This mixed methods study aimed to explore clinicians' perceptions of TKA compared to AKA.
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Mindfulness and CBT: a conceptual integration bridging ancient wisdom and modern cognitive theories of psychopathology.
Front Psychol
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Department of Psychological Science, Kennesaw State University, Kennesaw, GA, United States.
With the rapid expansion of mindfulness and its incorporation into the "third wave" of Cognitive Behavioral Therapy (CBT), there has been evident confusion about what mindfulness is and how it relates to this broader category of interventions. In this article, I define mindfulness and CBT, and differentiate them while highlighting their substantial overlap. Specifically, I discuss the Buddhist Psychological Model and how it relates to the foundational cognitive model, demonstrating the common threads that run across these seemingly disparate philosophies.
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