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Genomic sequence analysis of a new reassortant infectious bursal disease virus from commercial broiler flocks in Central China. | LitMetric

AI Article Synopsis

  • The study details the complete nucleotide sequence of a new reassortant strain of infectious bursal disease virus (IBDV) identified in broiler flocks in China.
  • The genome is made up of two segments, A (3,232 nucleotides) and B (2,652 nucleotides), with origins from different strains: segment A from the vaccine strain B87 and segment B from the virulent strain OKYM.
  • This finding indicates the emergence of a novel IBDV strain in nature, highlighting potential implications for poultry health and vaccine effectiveness.

Article Abstract

We report the complete nucleotide sequence of a reassortant infectious bursal disease (IBD) virus (IBDV) HN isolate from commercial broiler flocks in central China. The genome consisted of 3,232 and 2,652 nucleotides in the coding regions of segments A and B, respectively. Alignment of both nucleotide and deduced amino acid sequences and phylogenetic analysis revealed that the genome segments A and B of HN were derived from the attenuated strain B87 and the VV strain OKYM. This is a new reassortant IBDV strain that has emerged in nature, involving segment A of a cell-culture-adapted attenuated vaccine strain B87.

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Source
http://dx.doi.org/10.1007/s00705-013-1682-yDOI Listing

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