In a recent study, Watanabe et al identify a novel enhancer in the fgf10 locus that is necessary and sufficient for expression in anterior second heart field. Their results suggest a competitive mechanism in which Isl1 and Nkx2-5 bind the enhancer to activate or repress this enhancer, respectively.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520998 | PMC |
| http://dx.doi.org/10.1161/CIRCRESAHA.113.301133 | DOI Listing |
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