The internal environment of high-yielding dairy cows was investigated in relation to 36 variables of the blood metabolic profile, blood serum, milk and urine, with the incidence of reduced titration acidity milk syndrome. The levels of variables were confronted with references values. At the same time the statistical significance of differences of arithmetical means from the reference mean was calculated. Correlation analysis of all variables yielded 630 correlation coefficients. Certain correlations were represented in form of correlogrammes. It has been demonstrated that the reduced titration acidity milk syndrome with the lowest values of 1.9 ml 0.25N NaOH per 100 ml occurred after administration of the feed ration deficient both in digestible crude protein and starch units (nutritive ratio 1:7.5) which contained unsafe grass haylage with a high content of ammonia (232.9 mg per 100 g). A highly significant negative correlation was proved to exist between lactose concentration and pH value of milk (r = -0.913); the regression equation (lactose) is 36.997--4.7536 (pH).
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Mol Genet Metab Rep
March 2025
Hayward Genetics Center, Dept of Pediatrics, Tulane University Medical School, New Orleans, LA, USA.
Objective: To provide insights and strategies for pegvaliase management in challenging cases with phenylketonuria (PKU) based on the first 5 years of experience with pegvaliase in real-world clinical practice.
Methods: Twelve PKU experts gathered during a one-day, in-person meeting to discuss clinical cases illustrating important lessons from their experiences treating patients with pegvaliase in real-world clinical practice. Challenges with pegvaliase experienced prior to and during treatment and corresponding strategies to overcome them were discussed.
Food Sci Nutr
January 2025
Food and Nutrition Policy and Planning Research Department, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences Tehran Iran.
This study aimed to estimate the quantity and trends of salt intake from industrial fermented dairy products, develop strategies to reduce salt content, and inform policymakers on promoting public health through healthier dairy options. A cross-sectional study was conducted on fermented dairy products. Seventy-nine random samples were selected, and the salt (NaCl %) content was determined by potentiometric titration after sample preparation and homogenization; also samples were analyzed for their moisture (oven drying method).
View Article and Find Full Text PDFHepatic ischemia-reperfusion injury (IRI) poses a significant threat to clinical outcomes and graft survival during hemorrhagic shock, hepatic resection, and liver transplantation. Current pharmacological interventions for hepatic IRI are inadequate. In this study, we identified ginsenoside Rk2 (Rk2), a rare dehydroprotopanaxadiol saponin, as a promising agent against hepatic IRI through high-throughput screening.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Hamamatsu University School of Medicine, Hamamatsu City, Chuo-ku, Japan.
Background: One method for noninvasive and simple urinary microalbumin testing is urine test strips. However, when visually assessing urine test strips, accurate assessment may be difficult due to environmental influences-such as lighting color and intensity-and the physical and psychological influences of the assessor. These complicate the formation of an objective assessment.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of General Surgery, Hui Ya Hospital of The First Affiliated Hospital, Sun Yat-Sen University, Huizhou, 516081, Guangdong, China.
Self-supported ultrathin PtRuMoCoNi high-entropy alloy nanowires (HEANWs) were synthesized by a one-pot co-reduction method, whose peroxidase (POD)-like activity and catalytic mechanism were elaborated in detail. As expected, the PtRuMoCoNi HEANWs showed excellent POD-like activity. It can quickly catalyze the oxidization of colorless 3,3',5,5'-tetramethylbenzidine (TMB) to blue TMB through decomposition of HO to superoxide radicals.
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