Low-grade inflammation and spinal cord injury: exercise as therapy?

Mediators Inflamm

Departamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, Brazil.

Published: August 2013

An increase in the prevalence of obesity in people with spinal cord injury can contribute to low-grade chronic inflammation and increase the risk of infection in this population. A decrease in sympathetic activity contributes to immunosuppression due to the lower activation of immune cells in the blood. The effects of physical exercise on inflammatory parameters in individuals with spinal cord injury have not been well described. We conducted a review of the literature published from 1974 to 2012. This review explored the relationships between low-grade inflammation, spinal cord injury, and exercise to discuss a novel mechanism that might explain the beneficial effects of exercise involving an increase in catecholamines and cytokines in people with spinal cord injury.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603299PMC
http://dx.doi.org/10.1155/2013/971841DOI Listing

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