Objective: Youth with type 1 diabetes mellitus are at risk for poor glycemic control as they age into adulthood. The aim of this study was to describe sociodemographic and clinical correlates of poor glycemic control associated with the transfer of care from pediatric to adult diabetes providers among a cohort of youth with type 1 diabetes diagnosed in adolescence.
Methods: Analyses included 185 adolescent participants with recently diagnosed type 1 diabetes in the SEARCH for Diabetes in Youth Study with pediatric care at baseline who were age ≥18 years at follow-up. Demographic and clinical factors were measured by survey and laboratory results. Survival analysis was used to estimate the age of transition. Logistic regression analysis assessed the association of demographic and clinical factors with the transition of care and poor glycemic control at follow-up.
Results: Fifty-seven percent of participants had transitioned to adult diabetes care providers by the follow-up visit. The estimated median age of transition of care was 20.1 years (95% confidence interval 19.8-20.4). Older age, lower baseline glycosylated hemoglobin, and less parental education were independently associated with increased odds of transition. The odds of poor glycemic control at follow-up were 2.5 times higher for participants who transitioned to adult care compared with those who remained in pediatric care.
Conclusions: Transferring from pediatric to adult care, experienced by more than half the sample, was associated with an increased risk of poor glycemic control at follow-up. These findings suggest that young adults need additional support when moving to adult care.
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http://dx.doi.org/10.1542/peds.2012-1450 | DOI Listing |
Nutr Hosp
March 2025
Facultad de Medicina. Universidad de Castilla-La Mancha.
Introduction: currently there are changes in lifestyle that have been modifying the nutritional culture, moving away from the Mediterranean diet (DMed) and acquiring a more sedentary lifestyle, a fact that has contributed to a significant increase in risk factors. (CVRF) such as obesity and type 2 diabetes mellitus (DM2), and consequently to a global increase in metabolic syndrome (MS) and cardiovascular diseases (CVD), which in the 21st century reinforces being the first cause of morbidity and mortality To reduce this pandemic, a multidisciplinary approach is required focused on the application of primary and secondary prevention strategies for modifiable CVRFs, focused on nutritional promotion and education through the promotion of a healthier lifestyle and diet from childhood, as the one that encompasses the MedD. This dietary pattern, together with physical exercise, has been shown to contribute to the primary and secondary prevention of DM2 and coexisting CVRF.
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
March 2025
Department of Public Health, Faculty of Medicine, Kandahar University, Kandahar, Afghanistan.
Background: Hypertension among patients with type 2 diabetes results in higher rates of cardiovascular complications and deaths. However, there is limited data on the prevalence of hypertension and its associated factors among patients with type 2 diabetes in Afghanistan.
Objective: Our study aims to determine the prevalence of hypertension and its associated factors among patients with type 2 diabetes in southern Afghanistan.
Cureus
February 2025
Department of Biochemistry, Government Medical College Narsampet, Sarwapuram, IND.
Background: Diabetes mellitus (DM) increases the risk of left ventricular dysfunction (LVD), which can progress to heart failure if undetected. Echocardiography, a non-invasive and cost-effective imaging tool, provides real-time assessment of left ventricular (LV) function and enables early detection of myocardial dysfunction using advanced techniques such as tissue Doppler imaging and strain analysis. Diabetic patients are particularly prone to LVD due to chronic hyperglycemia, insulin resistance, and systemic inflammation, leading to myocardial fibrosis, microvascular dysfunction, and oxidative stress.
View Article and Find Full Text PDFBMC Infect Dis
March 2025
Department of Tuberculosis, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, 211132, China.
Objective: Globally, Tuberculosis(TB) with type 2 diabetes mellitus (T2DM) is becoming increasingly serious, especially the emergence of rifampicin-susceptible and isoniazid-resistant tuberculosis (Hr-TB), which increases the difficulty of treatment and the burden of disease. Therefore, this single-center retrospective cohort study analyzed risk factors of Hr-TB in adult patients with T2DM and pulmonary tuberculosis (PTB) in Nanjing to guide clinical practice and improve the long-term prognosis of patients.
Methods: The clinical data of 279 adult inpatients diagnosed with culture-positive PTB and T2DM in the Second Hospital of Nanjing from January 2019 and December 2021 were collected.
J Pharm Bioallied Sci
December 2024
Department of Biochemistry, Shadan Institute of Medical Sciences, Teaching Hospital and Research Centre, Hyderabad, Telangana, India.
Background: This prospective study investigates the association between triglyceride (TG) levels and HbA1c values with different stages of invasive ductal breast cancer (IDC) in female patients. Metabolic alterations, including dyslipidemia and hyperglycemia, are increasingly recognized as potential factors associated with cancer progression.
Methods: A total of 150 female patients diagnosed with IDC were included in the study, categorized into four stages of the disease.
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