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Association between serum albumin levels at admission and clinical outcomes in pediatric intensive care units: a multi-center study.
BMC Pediatr
December 2024
Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Turkey.
Background: Albumin, a vital component in regulating human blood oncotic pressure, plays an important role in the prediction of prognosis in pediatric patients.Previous research identified significant differences in serum albumin levels of healthy and critically ill children.
Methods: The present study aims to investigate the correlation between albumin levels measured during pediatric intensive care unit(PICU) admission and clinical outcomes.
Management of severe pediatric Guillain-Barré syndrome in a low-income country: efficacy and safety of therapeutic plasma exchange in pediatric patients: a retrospective study.
BMC Pediatr
December 2024
Faculty of Medicine, Al-Baath University, Al-Sham Street, Homs, Syria.
Background: Guillain-Barré syndrome (GBS) is an autoimmune disease that affects the peripheral nervous system leading to motor, sensory, and sometimes autonomic manifestations. Therapeutic plasma exchange (TPE), which involves the selective removal of pathological molecules, such as auto-antibodies, from plasma, has proven to be safe and effective in adults with GBS. However, its application in pediatric patients lacks sufficient evidence.
View Article and Find Full Text PDFObjective: Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..
Patients And Methods: Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020.
Evaluating the safety and efficacy of plasma therapy/plasmapheresis for systemic sclerosis - A comprehensive systematic review.
Transfus Apher Sci
November 2024
Faculty of Medicine, University of Khartoum, Khartoum 11111, Sudan. Electronic address:
Article Synopsis
- Systemic sclerosis (SSc) is an autoimmune disease causing fibrosis in various organs and has uncertain origins, but plasma therapy may help manage its symptoms.
- The systematic review analyzed 15 studies that highlighted the potential benefits of plasma therapy, especially in early-stage SSc and specific complications, although results were inconsistent across studies.
- While plasma therapy shows promise in alleviating SSc symptoms with few side effects, further research is needed to fully understand its effectiveness and mechanisms.
Convalescent plasma therapy for COVID-19 - Donor selection strategies and establishment of a plasma bank.
New Microbes New Infect
December 2024
Meilahti Vaccine Research Center, MeVac, Department of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Background: Early in the COVID-19 pandemic, convalescent plasma (CP) emerged as a potentially effective treatment neutralising SARS-CoV-2. Early CP therapy with high neutralising antibody (NAb) titre may benefit COVID-19 outpatients and, in sufficient quantities even some hospitalised patients. This study details the process of setting up a CP bank, containing high- and low-titre CP for a clinical trial.
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