Samarium-153-lexidronam therapy for metastatic bone pain.

J Pain Palliat Care Pharmacother

Pain Unit, Hospital Universitari Son Espases, Palma de Mallorca, Spain .

Published: March 2013

Multidisciplinary management may offer alternative therapeutic strategies in patients. Bone-seeking radiopharmaceuticals offered alongside traditional approaches to analgesia may be useful in the treatment of metastatic bone pain. A case of metastatic bone pain in which (153)Sm-lexidronam therapy was used is presented. Minimal side effects, as well as a reduction in opioid use (via patient-controlled analgesia), were observed in this case.

Download full-text PDF

Source
http://dx.doi.org/10.3109/15360288.2012.760705DOI Listing

Publication Analysis

Top Keywords

metastatic bone
12
bone pain
12
samarium-153-lexidronam therapy
4
therapy metastatic
4
pain multidisciplinary
4
multidisciplinary management
4
management offer
4
offer alternative
4
alternative therapeutic
4
therapeutic strategies
4

Similar Publications

Objectives: Maxillary transverse deficiency is a common malocclusion frequently observed in orthodontic clinics. Miniscrew-assisted rapid palatal expansion (MARPE) not only produces greater skeletal expansion but also offers advantages such as simple miniscrew implantation without flap elevation, enhanced patient comfort, and an expanded age range and indications for palatal expansion. However, the fixed connection between the expander and the miniscrews makes the expander difficult to remove, significantly hindering its clinical application.

View Article and Find Full Text PDF

Pituitary neuroendocrine tumors (PitNETS) are common intracranial tumors, but extrasellar or ectopic PitNETS are very rare and supposed to originate from some pituitary remnants. They are mostly found in sphenoidal sinus. But particularly, ectopic clival PitNETS are highly aggressive and can cause bone invasion and can be misdiagnosed as other lesions of the skull base such as chordomas.

View Article and Find Full Text PDF

Microfluidic isolation and release of live disseminated breast tumor cells in bone marrow.

PLoS One

March 2025

Department of Mechanical and Aerospace Engineering, Interdisciplinary Microsystems Group, Gainesville, Florida, United States of America.

Breast cancer represents a significant therapeutic challenge due to its aggressive nature and resistance to treatment. A major cause of treatment failure in breast cancer is the presence of rare, low-proliferative disseminated tumor cells (DTCs) in distant organs including the bone marrow. This study introduced a microfluidic-based approach to improve the immunodetection and isolation of these rare DTCs for downstream analysis, with an emphasis on optimizing immunocapture, release, and enrichment methods of live DTCs as compared to the standard approach for blood-borne circulating tumor cells (CTCs).

View Article and Find Full Text PDF

Background: Neuroendocrine carcinomas (NECs) are rare tumors from hormone-secreting neuroendocrine cells, often within the gastrointestinal tract. The authors report what is, to their best knowledge, the first case of a small intestine NEC metastasizing to the temporomandibular joint (TMJ).

Case Description: A 60-year-old man came to the oral medicine, oncology, and orofacial pain clinic with a chief concern of left-sided jaw pain.

View Article and Find Full Text PDF

Purpose: The proximal femur is a frequent site of cancer dissemination in the extremities. Patients treated surgically for skeletal metastases have poorer overall health compared to other orthopedic patients, with only one-third expected to survive two years post-surgery. Choosing a treatment that minimizes revision risk and ensures the implant outlives the patient is therefore crucial.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!