Enantioselective relay catalytic cascade intramolecular hydrosiloxylation and Mukaiyama aldol reaction.

Chemistry

Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, PR China.

Published: May 2013

Cascading chemistry! The first practical relay catalytic cascade intramolecular hydrosiloxylation of arylacetylene and asymmetric Mukaiyama aldol reaction has been established to give synthetically useful products in high yields and with excellent ee (see scheme).

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Source
http://dx.doi.org/10.1002/chem.201300702DOI Listing

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