Introduction: Fibro-osseous lesions constitute a rare benign type of pathology with a non-odontogenic lineage that affect the craniofacial area. According to Waldrom's classification, these lesions are divided into: fibrous dysplasia (FD), cemento-ossifying fibroma (COF) and desmoplastic fibroma (DF).
Material And Methods: A retrospective study was performed on patients diagnosed with fibro-osseous lesions of the craniofacial area at the Hospital Universitario La Fe, Valencia, during 1987-2009. A total of 19 cases were collected: 15 cases compatible with an FD diagnosis, 3 cases with a COF diagnosis and 1 case with a DF diagnosis.
Results: In the differential diagnosis, entities having similar clinical manifestations in the maxillofacial area with possible involvement of teeth or manifestations present as an asymptomatic radiolucent image should be ruled out. We hereby present the management and development of patients treated in our hospital for fibro-osseous lesions.
Conclusions: Fibro-osseous lesions share many clinical and radiological characteristics in common, with histological features confirming the nature of the lesion. Management of patients should be individualized and case-specific, assessing the clinical evolution of each case and taking into account the benign nature and growth behavior of this type of tumors.
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http://dx.doi.org/10.4317/medoral.18289 | DOI Listing |
Cureus
December 2024
Department of Reconstructive and Maxillofacial Surgery, Hassan II University Hospital of Fez, Fez, MAR.
Florid osseous dysplasia (FOD) is a rare, benign fibro-osseous lesion primarily involving the mandible and maxilla, with a higher prevalence in middle-aged women of African or Asian descent. This article presents a case of mandibular FOD complicated by secondary infection, emphasizing clinical presentation, diagnostic challenges, and treatment strategies. The unique radiographic features of FOD necessitate careful differential diagnosis to prevent misdiagnosis with other jaw lesions.
View Article and Find Full Text PDFOral Dis
December 2024
Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Objective: To assess the sclerostin, β-catenin, and tryptase expression in fibro-osseous lesions (FOL) of the jaws.
Subjects And Methods: Immunohistochemistry analysis was performed for these proteins on FOL and non-lesional bone. The sclerostin-positive cells were scored from 0 (no expression) to 3 (high expression).
Curr Opin Otolaryngol Head Neck Surg
February 2025
Department of Otolaryngology - Head & Neck Surgery, University of Florida, Gainesville, Florida, USA.
Purpose Of Review: Fibro-osseous lesions (FOL) are benign, slow-growing lesions that are often incidentally discovered in the sinonasal cavity. They may necessitate surgical resection in patients with postobstructive sinusitis, or in cases of cranial nerve and orbital compression. We examine the recent advancements in otolaryngology relating to diagnostic characteristics and treatments for FOL, with emphasis on new technologies to improve outcomes and reduce recurrence.
View Article and Find Full Text PDFCranial fibrous dysplasia (FD) syndrome is a benign, rare, and idiopathic skeletal disorder characterized by the replacement and expansion of medullary bone by disorganized fibro-osseous tissue. Trigeminal neuralgia (TN) is most commonly caused by vascular compression at the trigeminal nerve root entry zone. Secondary TN caused by cranial FD syndrome is extremely rare.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
December 2024
Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.
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