AI Article Synopsis
- The study compared the diagnostic performance of 14-gauge and 16-gauge core needle biopsies (CNB) for breast lesions detected by ultrasound.
- A total of 1024 paired CNB and open surgical biopsy (OSB) results were analyzed, showing high sensitivity (92.9%) and specificity (99.7%) for the CNB procedures.
- The results indicated that 14-gauge needles had better overall accuracy and lower rates of underestimation and false negatives compared to 16-gauge needles, recommending the use of 14-gauge for ultrasound-guided biopsies.
Article Abstract
Background/objective: Core needle biopsy (CNB) was widely used in the diagnosis of ultrasound-detectable breast lesions. We aimed at assessing the diagnostic performance differences between 14- and 16-gauge ultrasound-guided core biopsies.
Methods: This retrospective study enrolled patients receiving CNB from January 2001 to December 2007. The results of 14- and 16-gauge breast CNBs were compared with pathology reports of open surgical biopsy (OSB).
Results: A total of 1024 paired CNB and OSB results were obtained from 1732 CNB procedures in 1630 patients.Those CNB results reached 92.9% sensitivity, 99.7% specificity, 5.96% underestimation, and 94.8% accuracy rates. There was no difference in sensitivity (p=0.17) or specificity (p=0.38) between 14- and 16-gauge needles. However, better overall accuracy (p=0.02), less underestimation (p<0.001), and lower false-negative (p=0.02) rates were found for the 14-gauge CNB.
Conclusion: Regarding accuracy and underestimation rates, a 14-gauge needle is preferred to a 16-gauge one in ultrasound-guided biopsies.
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| http://dx.doi.org/10.1016/j.asjsur.2012.09.003 | DOI Listing |
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