Background: The Clinical Outcomes in Routine Evaluation--Outcome Measure (CORE-OM) is a 34-item instrument developed to monitor clinically significant change in out-patients. The CORE-OM covers four domains: well-being, problems/symptoms, functioning and risk, and sums up in two total scores: the mean of All items, and the mean of All non-risk items. The aim of this study was to examine the psychometric properties of the Norwegian translation of the CORE-OM.
Methods: A clinical sample of 527 out-patients from North Norwegian specialist psychiatric services, and a non-clinical sample of 464 persons were obtained. The non-clinical sample was a convenience sample consisting of friends and family of health personnel, and of students of medicine and clinical psychology. Students also reported psychological stress. Exploratory factor analysis (EFA) was employed in half the clinical sample. Confirmatory (CFA) factor analyses modelling the theoretical sub-domains were performed in the remaining half of the clinical sample. Internal consistency, means, and gender and age differences were studied by comparing the clinical and non-clinical samples. Stability, effect of language (Norwegian versus English), and of psychological stress was studied in the sub-sample of students. Finally, cut-off scores were calculated, and distributions of scores were compared between clinical and non-clinical samples, and between students reporting stress or no stress.
Results: The results indicate that the CORE-OM both measures general (g) psychological distress and sub-domains, of which risk of harm separates most clearly from the g factor. Internal consistency, stability and cut-off scores compared well with the original English version. No, or only negligible, language effects were found. Gender differences were only found for the well-being domain in the non-clinical sample and for the risk domain in the clinical sample. Current patient status explained differences between clinical and non-clinical samples, also when gender and age were controlled for. Students reporting psychological distress during last week scored significantly higher than students reporting no stress. These results further validate the recommended cut-off point of 1 between clinical and non-clinical populations.
Conclusions: The CORE-OM in Norwegian has psychometric properties at the same level as the English original, and could be recommended for general clinical use. A cut-off point of 1 is recommended for both genders.
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http://dx.doi.org/10.1186/1471-244X-13-99 | DOI Listing |
Child Abuse Negl
December 2024
Beijing Key Laboratory of Applied Experimental Psychology, National Demonstration Center for Experimental Psychology Education (Beijing Normal University), Faculty of Psychology, Beijing Normal University, Beijing 100875, China.
Background: Individuals with a history of childhood maltreatment commonly experience the co-occurrence of complex post-traumatic stress disorder (CPTSD) and depression, but the underlying mechanisms of their comorbidities remain unclear.
Methods: We recruited 2740 college students, including 1366 who experienced childhood maltreatment to assess the co-occurrence network of CPTSD and depression symptoms. We constructed a Gaussian graphical model to visualize the associations between symptoms and a directed acyclic graph to explore inferred relationships among symptoms.
J Pharm Sci
December 2024
Certara UK Ltd., Certara Predictive Technologies Division, 1 Concourse Way, Level 2-Acero, Sheffield, S1 2BJ, United Kingdom. Electronic address:
Predicting steady-state volume of distribution (V) is a key component of pharmacokinetic predictions and often guided using preclinical data. However, when bottom-up prediction from physiologically-based pharmacokinetic (PBPK) models and observed V misalign in preclinical species, or predicted V from different models varies significantly, no consensus exists for selecting models or preclinical species to improve the prediction. Through systematic analysis of V prediction across rat, dog, monkey, and human, using common methods, a practical strategy for predicting human V, with or without integration of preclinical PK information is warranted.
View Article and Find Full Text PDFChild Abuse Negl
December 2024
Department of Psychology, Hunan Normal University, Changsha, China; Cognition and Human Behavior Key Laboratory of Hunan Province, Hunan Normal University, Changsha, China; Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, China; Center for Mind & Brain Sciences, Hunan Normal University, Changsha, China. Electronic address:
Background: Accumulating literature has found a close relation between early life adversity (ELA) and anxiety. However, previous studies did not rule out the high co-occurrence of different types of ELA when exploring the association of ELA and anxiety. In the present study, we carried out network analysis based on a cross-sectional sample and longitudinal sample to investigate the relationship between ELA and anxiety symptoms in non-clinical populations over time.
View Article and Find Full Text PDFSchizophr Res
December 2024
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, United States of America.
Background: Social Support has been found to contribute to lower mental illness burden, higher treatment adherence, enhanced social functioning, and better quality of life. Individuals with schizophrenia report lower social support compared to non-clinical populations, yet the factors contributing to this discrepancy are not fully clear. Specifically, the person-related variables that may enhance or hinder SS in people with schizophrenia are unknown.
View Article and Find Full Text PDFEat Disord
December 2024
Department of Psychological Sciences, Swinburne University of Technology, Melbourne, VIC, Australia.
Objectification theory posits that self-objectification can lead to disordered eating, with significant positive correlations between self-objectification and eating disorder (ED) psychopathology found in women in both clinical and non-clinical samples. Maladaptive rumination is another process frequently associated with EDs, but its relationship with self-objectification and ED psychopathology needs further investigation. Our aim was to conduct a preliminary test to investigate whether maladaptive rumination mediated the relationship between self-objectification and ED psychopathology in women.
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