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Objective: The study aims to elucidate the mechanisms underlying plaque growth by analyzing the variations in hemodynamic parameters within the plaque region of patients' carotid arteries before and after the development of atherosclerotic lesions.

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Diagnostic approach in Giant cell arteritis.

Autoimmun Rev

January 2025

Rheumatology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; University of Modena and Reggio Emilia, Modena, Italy. Electronic address:

Giant cell arteritis (GCA), also known as temporal arteritis, is the most common form of vasculitis in the elderly. While initially described as involving the temporal arteries, GCA can also affect the aorta and its major branches. Despite the increased use of imaging modalities and the availability of temporal artery biopsy, diagnosing GCA remains challenging.

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Cerebral arteriovenous malformations (AVMs) are tangles of abnormal vessels with early arteriovenous (AV) shunting that can lead to intracerebral hemorrhage, seizures, neurologic deficit, or headache. To date, only a few cases of carcinomas metastasizing to pre-existing cerebral AVMs have been reported in the literature. However, renal clear cell carcinoma (RCC) brain metastases that exhibit early AV shunting, where AVM pathology is not present, are extremely rare.

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How I do it - focused Sylvian approach for clipping of middle cerebral artery aneurysms.

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Department of Neurosurgery, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.

Background: The Focused Sylvian Approach (FSA) is a refined, minimally invasive technique for clipping small to medium-sized middle cerebral artery (MCA) aneurysms, prioritizing safety and aesthetics.

Method: The craniotomy remains confined to the superior temporal line, with the incision concealed within the temporal muscle. The Sylvian fissure is carefully dissected to preserve venous structures.

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The human cerebral cortex is known for its hemispheric specialization, which underpins a variety of functions and activities. However, it is not well understood if similar lateralization exists within the deep gray matter nuclei, such as the basal ganglia (BG) and thalamus, and their associated arteries, including the lenticulostriate arteries (LSAs). To explore this, we analyzed images from 7T MRI scans of 40 healthy young individuals.

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