Clinical efficacy of 7 day reamberin therapy of abstinence syndrome was compared in 32 alcoholics with concomitant exogenous organic brain lesions (F 10.2, mean age 41.2 +/- 6.3 YR) and 46 control patients given no treatment. Reamberin accelerated reduction of somatovegetative manifestations of abstinence syndrome with subsequent normalization of its affective components. It is concluded that combined therapy including reamberin significantly reduced severity of endogenous intoxication in alcoholics suffering exogenous organic brain lesions.

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