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Fructose-Modified Chitosan/Gelatin 3D Composite Sponge for Enhanced Rapid Hemostasis.

Biomacromolecules

January 2025

Institute of Chemicobiology and Functional Materials, School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, 200 Xiao Ling Wei, Nanjing, Jiangsu Province 210094, China.

Managing uncontrolled and noncompressible bleeding presents a major challenge in emergency trauma care. Methods to halt bleeding quickly and efficiently, without applying direct pressure on the wound, have become a key focus of research. Herein, a novel fructose-modified chitosan/gelatin composite sponge has been developed, exhibiting high elasticity, low rebound pressure, and excellent cell compatibility.

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Background: Cardiometabolic comorbidities such as obesity, diabetes, and hypertension are highly prevalent in heart failure (HF). We aimed to examine the association between severity of cardiometabolic comorbidities and hospitalization in patients with HF.

Methods: In a retrospective electronic health record-based cohort of adults 18 with HF, we categorized individuals based on the number of severe cardiometabolic comorbidities, including hypertension, diabetes, and obesity.

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Wearable optical coherence tomography angiography probe with extended depth of field.

J Biomed Opt

January 2025

Tsinghua University, State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Beijing, China.

Significance: Optical coherence tomography (OCT) is widely utilized to investigate brain activities and disorders in anesthetized or restrained rodents. However, anesthesia can alter several physiological parameters, leading to findings that might not fully represent the true physiological state. To advance the understanding of brain function in awake and freely moving animals, the development of wearable OCT probes is crucial.

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Insulin degludec 100 U/mL for treatment of spontaneous diabetes mellitus in dogs.

J Vet Intern Med

January 2025

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.

Background: The advantages of insulin degludec 100 U/mL (IDeg100) in the treatment of diabetes mellitus (DM) include consistent release, predictable glucose-lowering effect, and minimal day-to-day variability.

Hypothesis/objectives: To describe the use of IDeg100 in dogs with DM, level of diabetic control and adverse effects.

Animals: Thirty-three client-owned dogs with DM.

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Background: Black people are more likely to have hypertension and report lower quality of care than White people. Patient-provider race concordance could improve perceived quality of care, potentially lessening disparities.

Objective: Investigate the association between patient-provider race concordance and patient-perceived quality of chronic disease care, as measured by the Patient Assessment of Chronic Illness Care (PACIC) scale.

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