The purpose of this article is to recommend positioning to reduce the effective and breast-absorbed-doses in paediatric scoliosis radiography. Effective and breast-absorbed-doses were evaluated using Monte Carlo simulations. Head directed towards the anode (HTA) positioning rather than head directed towards the cathode (HTC) reduces the effective dose to 98 % in anterior posterior (AP), 98 % in left lateral (L LAT) and 96 % in right lateral (R LAT) projections. HTC in posterior anterior (PA) projection contributes a smaller effective dose than HTA by <1 %, but causes a breast-absorbed-dose excess (HTA/HTC breast dose ratios were 85 and 87 % for 10- and 15-y- olds). With the preferential HTA positioning, R LAT projection reduced effective dose to 85 and 84 % compared with L LAT, for 10 and 15 y olds. AP-HTA projection caused 183 and 181 % larger effective doses than PA-HTA and breast-absorbed-dose excesses of 550 and 879 %, for 10 and 15 y olds. When possible, use R LAT and PA projections to reduce effective dose; Of secondary importance, whenever possible, use HTA, with the exception that for 15 y olds, PA-HTC reduces the effective dose more than HTA (1 %) but causes a breast-absorbed-dose excess.
Introduction: Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented. The present study assessed the effectiveness of a novel topical formulation, referred to as retinol topical formulation (RTF), to improve the quality of skin health.
Copper-based sulfides are attractive candidates for NIR I and II responsive photothermal therapy but often suffer from high hydrophobicity, suboptimal photothermal conversion, and poor biostability and biocompatibility. In the present work, a rapid, one-pot synthesis method was developed to obtain Au-doped CuS (ACSH NDs) dual plasmonic nanodots. ACSH NDs exhibit excellent peroxidase-like catalytic activity for pH-responsive OH radical generation along with efficient glutathione depletion under tumor microenvironment mimicking conditions.
Creatine monohydrate supplementation (CrM) is a safe and effective intervention for improving certain aspects of sport, exercise performance, and health across the lifespan. Despite its evidence-based pedigree, several questions and misconceptions about CrM remain. To initially address some of these concerns, our group published a narrative review in 2021 discussing the scientific evidence as to whether CrM leads to water retention and fat accumulation, is a steroid, causes hair loss, dehydration or muscle cramping, adversely affects renal and liver function, and if CrM is safe and/or effective for children, adolescents, biological females, and older adults.
Unlabelled: Valproic acid (VPA) demonstrates teratogenic effects during pregnancy. Prenatal exposure to VPA may result in autism spectrum disorder (ASD) -like phenotypes. Apigenin, a natural flavonoid, has been shown to have neuroprotective impacts due to its antioxidant properties.
Based on theoretical premises of ecological systems theory and the compensatory hypothesis, a subset of data from the Family Life Project ( = 773), a population-based study of rural families with low incomes, were used to test for associations between maternal literacy in infancy and children's academic outcomes and teacher-reported problem behaviors in kindergarten. A second aim tested whether increased time in child care averaged from 6-36 months moderated such relations. Results indicated that maternal literacy was significantly positively related to academic outcomes ( = .
