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The child behind the victim: Survivor experiences of children's harmful sexual behavior.

Child Abuse Negl

March 2025

University of Melbourne, Department of Social Work, Level 6, Alan Gilbert Building, 161 Barry Street, Carlton, Victoria, 3053, Australia. Electronic address:

Background: At least 50 % of child sexual abuse involves perpetration by children, referred to as "harmful sexual behavior". Recently, the sexual abuse sector has focused, importantly, on the child behind the "perpetrator" to support developmentally-appropriate and trauma-informed practice. However, the experiences of victim-survivors of children's sexually abusive behavior are underexplored.

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Abusive head trauma (AHT) has been defined as an injury to the skull or intracranial contents of a baby or young child (age less than five years) due to inflicted blunt impact and/or forceful shaking. It has a substantial impact, such as blindness and severe developmental delay in the short and long run. We searched PubMed, Cochrane, Embase, and Google Scholar databases for articles published between January 2001 and December 2021.

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Background: Domestic violence (DV) is a public health problem in the United States. Emergency physicians are often the first providers to see patients needing acute care for injuries sustained secondary to DV and are an important part of the healthcare workforce for underserved populations seeking help. While much has been published about the need for better identification and care of this population, little is known about the current prevalence and characterization of DV curricula in accredited emergency medicine residency programs.

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Importance: Child sexual abuse (CSA) impacts 15% of girls and 8% of boys worldwide, incurring high public costs and devastating consequences for survivors. US incidence rates have stagnated over the past 15 to 20 years, signaling a dire need for innovation in primary prevention. In 2024, the US Preventive Services Task Force reported that there is insufficient evidence for the effectiveness of child abuse preventive strategies, and none have shown decreases in incidence rates at the population level.

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Neuroactive Steroids and the Pathophysiology of PTSD: Biomarkers for Treatment Targeting.

Neurosci Biobehav Rev

February 2025

VA National Center for PTSD, Women's Health Science Division, VA Boston Healthcare System, Boston, MA 02130, USA; Department of Psychiatry, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, 02118, USA.

Posttraumatic stress disorder (PTSD) is a disabling psychiatric disorder that arises after acute or chronic exposure to threatened death, serious injury, or sexual violence. The pathophysiology of PTSD is complex and involves dysregulation of multiple interacting brain regions and neurobiological systems including the sympathetic nervous system, the hypothalamic-pituitary-adrenal (HPA) axis, and the immune system. Deficient biosynthesis of neurosteroids that positively modulate GABA receptor function, including allopregnanolone (Allo) and its equipotent stereoisomer pregnanolone (PA), also affects a subpopulation of individuals with PTSD and is associated with increased PTSD risk, severity, chronicity and treatment resistance.

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