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The Road to Commercializing Optical Metasurfaces: Current Challenges and Future Directions.
ACS Nano
January 2025
Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Optical metasurfaces, components composed of artificial nanostructures, are recognized for pushing boundaries of wavefront manipulation while maintaining a lightweight, compact design that surpasses conventional optics. Such advantages align with the current trends in optical systems, which demand compact communication devices and immersive holographic projectors, driving significant investment from the industry. Although interest in commercialization of optical metasurfaces has steadily grown since the initial breakthrough with diffraction-limited focusing, their practical applications have remained limited by challenges such as, massive-production yield, absence of standardized evaluation methods, and constrained design methodology.
View Article and Find Full Text PDFRobot-assisted Kidney Transplantation in Patients Undergoing Cystectomy with Urinary Diversion: First Cases Reported by the ERUS-RAKT Working Group.
Eur Urol Open Sci
January 2025
Department of Urology, Hospital Universitari de Bellvitge, Barcelona, Spain.
The indication for kidney transplantation over a urinary diversion (UD) for patients with severe lower urinary tract dysfunction and end-stage renal disease is a controversial issue. Thanks to advances in robot-assisted kidney transplant (RAKT) programs, the boundaries are being pushed further. We present the first RAKT series reported for patients undergoing simple cystectomy and UD for benign bladder disease.
View Article and Find Full Text PDFIntroduction to the special issue: A festschrift for Janice Kiecolt-Glaser - At the origin of stress and immunity.
Compr Psychoneuroendocrinol
November 2024
Department of Psychological Sciences, Rice University, Houston, TX, USA.
This special issue of pays tribute to Janice Kiecolt-Glaser's groundbreaking career and marks her well-earned retirement. As a leader in human psychoneuroimmunology (PNI), Kiecolt-Glaser transformed the domain by showing that everyday stressors, along with significant life events, can significantly affect the immune system. Her groundbreaking research on informal dementia caregivers revealed the detrimental effects of chronic psychological stress, including delayed wound healing, virus reactivation, heightened proinflammatory cytokine levels, and weakened vaccine responses.
View Article and Find Full Text PDFPushing the boundaries: future directions in the management of spinal muscular atrophy.
Trends Mol Med
January 2025
MDUK Oxford Neuromuscular Centre, Department of Paediatrics, University of Oxford, Oxford, OX3 9DU, UK; NIHR Oxford Biomedical Research Centre, Oxford, OX3 9DU, UK; Neuromuscular Centre, Division of Paediatrics, University Hospital of Liège and University of Liège, 4000, Liège, Belgium. Electronic address:
Spinal muscular atrophy (SMA) is a devastating, degenerative, paediatric neuromuscular disease which until recently was untreatable. Discovery of the responsible gene 30 years ago heralded a new age of pioneering therapeutic developments. Three disease-modifying therapies (DMTs) have received regulatory approval and have transformed the disease, reducing disability and prolonging patient survival.
View Article and Find Full Text PDFA Brief History of Cell Culture: From Harrison to Organs-on-a-Chip.
Cells
December 2024
Department of Genetic, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14040-904, Brazil.
This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux's seminal experiments in the 1880s, followed by the pioneering efforts of Ross Granville Harrison, who initiated groundbreaking experiments that fundamentally shaped the landscape of cell culture in the early 20th century. Carrel's influential contributions, notably the immortalization of chicken heart cells, have marked a significant advancement in cell culture techniques.
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