Covalent multistep coating of poly(methylpentene), the membrane material in lung ventilators, by using a copper-free "click" approach with a modified cyclic RGD peptide, leads to a highly biocompatible poly(methylpentene) surface. The resulting modified membrane preserves the required excellent gas-flow properties while being densely seeded with lung endothelial cells.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596089PMC
http://dx.doi.org/10.3762/bjoc.9.33DOI Listing

Publication Analysis

Top Keywords

biocompatible artificial
4
artificial lung
4
lung covalent
4
covalent functionalization
4
functionalization poly4-methylpent-1-ene
4
poly4-methylpent-1-ene tpx
4
tpx crgd
4
crgd pentapeptide
4
pentapeptide covalent
4
covalent multistep
4

Similar Publications

Dental titanium implants and their surface modifications markedly improve implant biocompatibility. However, studies evaluating the mechanical biocompatibility of implants are scarce. In particular, the analysis of mechanical biocompatibility deficiencies leading to stress shield-induced bone resorption.

View Article and Find Full Text PDF

Carbon dot embedded hybrid microgel from synthesis to sensing: Experimental and theoretical approach.

Anal Chim Acta

February 2025

Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh, 160014, India; Department of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Simhat, Haringhata, West Bengal, 741249, India. Electronic address:

Background: The intellectual progress in fabricating artificial probes for selective appraisal of biologically admissible amino acids has displayed exponential growth in recent era.The neoteric era in material science has witnessed the significant application of carbon quantum dots (CQDs). However, the hybrid microgel of CQDs was less explored.

View Article and Find Full Text PDF

Optimal submicron roughness for balancing degradation behavior, immune modulation, and microbial adhesion on zinc-based barrier membranes.

Biomater Adv

December 2024

Department of Prosthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Medical University, Guangzhou 510180, China; Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou 510180, China. Electronic address:

Metallic zinc (Zn) has been demonstrated to be a promising alternative to barrier membrane materials for guided bone regeneration. Surface roughness significantly affects the properties of degradable Zn-based metals, especially within the Janus micro-environments of tissue regeneration. However, the effects of optimal surface roughness on Zn remain unknown.

View Article and Find Full Text PDF

Innovative perspectives on metal free contrast agents for MRI: Enhancing imaging efficacy, and AI-driven future diagnostics.

Acta Biomater

January 2025

Institute of Smart Biomedical Materials, School of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, PR China. Electronic address:

The U.S. Food and Drug Administration (FDA) has issued a boxed warning and mandated additional safety measures for all gadolinium-based contrast agents (GBCAs) used in clinical magnetic resonance imaging (MRI) due to their prolonged retention in the body and associated adverse health effects.

View Article and Find Full Text PDF

Natural bone is a self-regenerating nanocomposite made of proteins and minerals. Such self-regenerative capacity can be negatively affected by certain diseases involving the bone or its surrounding tissues. Our study assesses the ability of bone grafting material to regenerate bone in animals who have artificially created critical-sized defects.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!