AI Article Synopsis
- The study aimed to compare the radiologic morphology of growth hormone-producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenomas (NFoma) using MRI in 100 cases.
- Differences were observed in MRI features, with GHoma showing more hypo-intensity on T2-weighted images and a greater tendency for inferior tumor extension.
- The location of the pituitary gland relative to the tumors also differed, being superior to GHoma and postero-superior to NFoma, confirming distinct growth characteristics between the two types of adenomas.
Article Abstract
Apart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenomas (NFoma). Pre-surgical magnetic resonance images (MRIs) were assessed in 50 cases of GHoma and 50 cases of NFoma. Geometric parameters on MRI were set in accordance with sellar anatomy. Intensity of T1-weighted image was not different between the two groups, but hypo-intensity of T2-weighted image was more frequently seen in GHoma. Predominant inferior extension of tumor was seen mostly in GHoma (88 vs. 38%). Extension of the tumor to the superior compartment of cavernous sinus was more frequent in NFoma. Pituitary gland was generally located superior to GHoma and postero-superior to NFoma. Growth characteristics of pituitary adenoma were confirmed to differ between GHoma and NFoma.
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| http://dx.doi.org/10.1007/s11102-013-0479-z | DOI Listing |
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