Objectives: At the end of the 1990s, as required by European Directive 92/57/EEC, two laws were enacted in Italy which laid down safety and health requirements for construction sites: Decree 494/96 and Decree 528/99. The aim is to evaluate the impact on injury rates due to actions performed by a group of eight regions that planned formalised programmes to enforce the laws around the year 2000.
Methods: Using the Work History Italian Panel-Salute integrated database, which extends from 1994 to 2005, total and serious injury rates were calculated for the construction sector. An interrupted time series analysis was applied to serious injury rates.
Results: During the 12 years under observation, at the national level the total and serious injury rates decreased while the number of employees increased. The results of the regression models indicate that in the period after the intervention the injury rates (×10 000 weeks worked) decreased by 0.21 per year more than in the period before the intervention (CI -0.41 to -0.01). The difference in pre-post trends is even larger after adjusting for external factors.
Conclusions: The intervention plans developed to enforce the two Italian decrees had an effect on the reduction in injury rates. The results showed that there was a decrease in injury rates that could not be explained by external factors. These findings highlight the importance of concrete initiatives to have employers and workers comply with regulatory safety standards.
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http://dx.doi.org/10.1136/oemed-2012-101087 | DOI Listing |
Eur J Emerg Med
September 2024
Department of Anaesthesiology and Intensive Care Medicine.
Background: Noncompressible truncal hemorrhage is a major contributor to preventable deaths in trauma patients and, despite advances in emergency care, still poses a big challenge.
Objectives: This study aimed to assess the clinical efficacy of trauma resuscitation care incorporating Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) compared to standard care for managing uncontrolled torso or lower body hemorrhage.
Methods: This study utilized a target trial design with a matched case-control methodology, emulating randomized 1 : 1 allocation for patients receiving trauma resuscitation care with or without the use of REBOA.
Chronic fracture-related infection is a complex, costly clinical problem with a wide spectrum of clinical presentations. The goals of treatment are infection control with a healed fracture covered by well-vascularized soft tissue and improvement of patient pain and function. Management is both medical, with culture-targeted antimicrobial agents, and surgical, requiring meticulous irrigation and débridement.
View Article and Find Full Text PDFmBio
December 2024
Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.
Unlabelled: Respiratory epithelial cells can survive direct infection by influenza viruses, and the long-term consequences of that infection have been characterized in a subset of proximal airway cell types. The impact on the cells that survive viral infection in the distal lung epithelia, however, is much less well-characterized. Utilizing a Cre-expressing influenza B virus (IBV) and a lox-stop-lox tdTomato reporter mouse model, we identified that alveolar type 2 (AT2) pneumocytes, a progenitor cell type in the distal lung, can survive viral infection.
View Article and Find Full Text PDFClin J Sport Med
January 2025
Department of Orthopaedic Surgery and Sports Medicine, Children's Mercy, Kansas City, Missouri; and.
Objective: To report injury epidemiology in youth male academy-level athletes in the United States.
Design: An observational study on injury occurrences and playing time over the 2019 to 2020, 2020 to 2021, and 2021 to 2022 soccer seasons.
Setting: Data collected from a single midwestern soccer academy in the United States in partnership with a tertiary care level I pediatric heath institution.
J Mater Chem B
January 2025
Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Cardiovascular diseases (CVDs) are the foremost cause of mortality worldwide, with incidence and mortality rates persistently climbing despite extensive research efforts. Innovative therapeutic approaches are still needed to extend patients' lives and preserve their health. In the present study, novel supramolecular nanomedicine with both nitric oxide (NO) and antioxidant releasing ability was developed to enhance therapeutic efficacy against vascular injuries.
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