Confined granular fluids, placed in a shallow box that is vibrated vertically, can achieve homogeneous stationary states due to energy injection mechanisms that take place throughout the system. These states can be stable even at high densities and inelasticities allowing for a detailed analysis of the hydrodynamic modes that govern the dynamics of granular fluids. By analyzing the decay of the time correlation functions it is shown that there is a crossover from a quasielastic regime in which energy evolves as a slow mode to an inelastic regime with energy slaved to the other conserved fields. The two regimes have well differentiated transport properties and in the inelastic regime the dynamics can be described by a reduced hydrodynamics with modified longitudinal viscosity and sound speed. The crossover between the two regimes takes place at a wave vector that is proportional to the inelasticity. A two-dimensional granular model, with collisions that mimic the energy transfers that take place in a confined system, is studied by means of microscopic simulations. The results show excellent agreement with the theoretical framework and allow validation of hydrodynamiclike models.
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http://dx.doi.org/10.1103/PhysRevE.87.022209 | DOI Listing |
Biomimetics (Basel)
January 2025
Group of Biomechatronics, Fachgebiet Biomechatronik, Technische Universität Ilmenau, D-98693 Ilmenau, Germany.
Anguilliform locomotion, an efficient aquatic locomotion mode where the whole body is engaged in fluid-body interaction, contains sophisticated physics. We hypothesized that data-driven modeling techniques may extract models or patterns of the swimmers' dynamics without implicitly measuring the hydrodynamic variables. This work proposes empirical kinematic control and data-driven modeling of a soft swimming robot.
View Article and Find Full Text PDFBiomimetics (Basel)
January 2025
College of Mechanical Engineering, Shenyang University of Technology, Shenyang 110870, China.
Using bidirectional fluid-structure interaction technology, the dorsal-ventral motion of the dolphin tail fin was simulated, and the feasibility of the numerical simulation method was validated through underwater motion experiments. This study investigated the effects of structural parameters and motion modes of bionic dolphin tail fins on their propulsion performance. The results show that flexible tail fins can enhance propulsion performance.
View Article and Find Full Text PDFNanoscale
January 2025
School of Sustainable Chemical, Biological and Materials Engineering, University of Oklahoma, Norman, OK 73019, USA.
Serum albumin has myriad uses in biotechnology, but its value as a nanocarrier or nanoplatform for therapeutics is becoming increasingly important, notably with albumin-bound chemotherapeutics. Another emerging field is the fabrication of biopolymeric nanoparticles using albumin as a building block to achieve highly-tunable nonimmunogenic capsules or scaffolds that may be cheaply and reliably produced. The aim of this study was to characterize and optimize the desolvation process used for fabrication of albumin nanoparticles under ambient conditions, studying both glutaraldehyde (GT) and glucose (GLU) as crosslinking agents and the effect of various synthesis conditions including pH, electrolyte concentration, and rate of desolvation on particle size and stability.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA, United States of America.
The administration of surfactant aerosol therapy to preterm infants receiving continuous positive airway pressure (CPAP) respiratory support is highly challenging due to small flow passages, relatively high ventilation flow rates, rapid breathing and small inhalation volumes. To overcome these challenges, the objective of this study was to implement a validated computational fluid dynamics (CFD) model and develop an overlay nasal prong interface design for use with CPAP respiratory support that enables high efficiency powder aerosol delivery to the lungs of preterm infants when needed (i.e.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
To simplify the composition and improve the efficacy of metal-phenolic network (MPN)-based nanomedicine, herein, we designed an MPN platform to deliver programmed death ligand-1 (PD-L1) antibody (anti-PD-L1) for combined tumor chemo/chemodynamic/immune therapy. Here, generation 5 poly(amidoamine) dendrimers conjugated with gossypol (Gos) through boronic ester bonds were used as a synthetic polyphenol to coordinate Mn, and then complexed with anti-PD-L1 to obtain the nanocomplexes (for short, DPGMA). The prepared DPGMA exhibited good water dispersibility with a hydrodynamic size of 166.
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