A new trend in the complex I research field.

Biol Chem

Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, 214A Anatomy/Chemistry Building, 36th and Hamilton Walk, Philadelphia, PA 19104-6059, USA.

Published: May 2013

To date, the 17th European Bioenergetics Conference (EBEC) in Freiburg, Germany (September 15-20, 2012) was the most exciting conference for the complex I (NADH-Q oxidoreductase) research field. A whole day of oral presentations was dedicated to complex I, including three plenary lectures and 11 symposium talks. In addition, 43 posters were dedicated to complex I projects. Here is a brief summary of an exciting paradigm shift from 'structure major' to 'structure plus function', clearly observed in the complex I research field.

Download full-text PDF

Source
http://dx.doi.org/10.1515/hsz-2013-0117DOI Listing

Publication Analysis

Top Keywords

complex field
8
dedicated complex
8
trend complex
4
field 17th
4
17th european
4
european bioenergetics
4
bioenergetics conference
4
conference ebec
4
ebec freiburg
4
freiburg germany
4

Similar Publications

Electric quadrupole traps are a leading technology for suspending charged objects ranging in size from single protons to atomic and molecular ions, and even to nano- and micron-sized bodies. If the levitated objects' charge distribution contains multipoles, the time-dependent trapping fields can significantly impact its rotational motion. Here, we experimentally observe the transition from librational motion to a regime where a microparticle rotates in sync with the trap drive.

View Article and Find Full Text PDF

We study image segmentation using spatiotemporal dynamics in a recurrent neural network where the state of each unit is given by a complex number. We show that this network generates sophisticated spatiotemporal dynamics that can effectively divide an image into groups according to a scene's structural characteristics. We then demonstrate a simple algorithm for object segmentation that generalizes across inputs ranging from simple geometric objects in grayscale images to natural images.

View Article and Find Full Text PDF

Multiphoton and Harmonic Imaging of Microarchitected Materials.

ACS Appl Mater Interfaces

January 2025

Laser Thermal Laboratory, Department of Mechanical Engineering, University of California, Berkeley, California 94720, United States.

Microadditive manufacturing has revolutionized the production of complex, nano- to microscale components across various fields. This work investigates two-photon (2P) and three-photon (3P) fluorescence imaging, as well as third-harmonic generation (THG) microscopy, to examine periodic microarchitected lattice structures fabricated using multiphoton lithography (MPL). By immersing the structures in refractive index matching fluids, we demonstrate high-fidelity 3D reconstructions of both fluorescent structures using 2P and 3P microscopy as well as low-fluorescence structures using THG microscopy.

View Article and Find Full Text PDF

IR-Driven Multisignal Conditioning for Multiplex Detection: Thermal-Responsive Triple DNA-Mediated Reconfigurable Photoelectrochemical/Photothermal Dual-Mode Strategy.

ACS Sens

January 2025

College of Chemistry, Jilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, Jilin University, Changchun 130012, China.

Superior to traditional multiplex photoelectrochemical (PEC) sensors, integrated multitarget assay on a single reconstructive electrode interface is promising in real-time detection through eliminating the need of specialized instrumentation and cumbersome interfacial modifications. Current interface reconstruction approaches including pH modulation and bioenzyme cleavage involve biohazardous and time-consuming operations, which cannot meet the demand for rapid, eco-friendly, and portable detection, which are detrimental to the development of multiplex PEC sensors toward portability. Herein, we report a pioneer work on IR-driven "four-to-one" multisignal conditioning to facile reconfigure electrode interface for multitarget detection via photoelectrochemical/photothermal dual mode.

View Article and Find Full Text PDF

Neohesperidin Improves Depressive-Like Behavior Induced by Chronic Unpredictable Mild Stress in Mice.

Neurochem Res

January 2025

Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, China.

Depression is a common and complex neuropsychiatric disorder affecting people of all ages worldwide, associated with high rates of relapse and disability. Neohesperidin (NEO) is a dietary flavonoid with applications in therapeutics; however, its effects on depressive-like behavior remain unknown. Here, we evaluated the effects of NEO on depressive-like behavior induced by chronic and unpredictable mild stress (CUMS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!