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[Amatoxin-containing mushroom poisoning: An update].
Rev Med Interne
July 2024
Centre antipoison de Paris, fédération de toxicologie (FeTox), hôpital Fernand-Widal, AP-HP, 200, rue du Faubourg-Saint-Denis, 75010 Paris, France; Université Paris-Cité, Inserm UMR-S 1144, optimisation thérapeutique en neuropsychopharmacologie, 4, avenue de l'Observatoire, 75006 Paris, France; UFR de médecine, université de Paris, 75006 Paris, France.
Amatoxin-containing mushroom poisoning occurs after consumption of certain mushroom species, of the genera Amanita, Lepiota and Galerina. Amanita phalloides is the most implicated species, responsible for over more than 90% of mushroom-related deaths. The α-amanitin is responsible for most of the observed effects.
View Article and Find Full Text PDFFurther development of a liquid chromatography-high-resolution mass spectrometry/mass spectrometry-based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestions.
Drug Test Anal
September 2021
Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, 66421, Germany.
Recently, we presented a strategy for analysis of eight biomarkers in human urine to verify toxic mushroom or Ricinus communis ingestions. However, screening for the full panel is not always necessary. Thus, we aimed to develop a strategy to reduce analysis time and by focusing on two sets of analytes.
View Article and Find Full Text PDFMedium Cut-Off Membrane Can Be a New Treatment Tool in Amanita phalloides Poisoning.
Wilderness Environ Med
June 2021
Department of Internal Medicine, Faculty of Medicine, Mugla University, Mugla, Turkey.
Mushroom poisoning is a common health problem that can be seen seasonally and geographically. Most mushroom poisoning requiring treatment worldwide is due to Amanita phalloides. Although liver failure and kidney injury are frequent, poisoning can also lead to more serious clinical situations, such as shock, pancreatitis, encephalopathic coma, cardiac failure, disseminated intravascular coagulation, and multiple organ dysfunction syndrome, and may cause death.
View Article and Find Full Text PDFMushroom Poisoning.
Dtsch Arztebl Int
October 2020
Luxembourg: Prof. Dr. Robert Wennig (formerly Laboratoire National de Santé- Toxicologie, Université du Luxembourg-Campus Limpertsberg); Department of Clinical Toxicology & Poison Control Center Munich, Klinikum rechts der Isar, School of Medicine, Technical University of Munich; GIZ-Nord Poisons Centre,Göttingen University Hospital Faculty of Medicine and University Hospital Cologne and Department of Forensic Toxicology, University Hospital Cologne.
Article Synopsis
- Poisonous mushrooms are often mistakenly consumed, leading to hospitalizations and consultations with poison information centers due to either misidentification or intentional use for their psychoactive effects.
- Mushroom poisoning can be categorized into two groups based on the time of symptom onset: a relatively harmless gastrointestinal syndrome occurring within six hours, and a life-threatening syndrome manifesting after six to 24 hours.
- Diagnosing mushroom poisoning relies more on clinical symptoms and detailed patient history than on analytical techniques, with expertise needed for accurate identification and understanding of the specific mushrooms involved.
Cardiac arrhythmias and cardiac arrest related to mushroom poisoning: A case report.
World J Clin Cases
August 2019
Department of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY 11219, United States.
Article Synopsis
- Mushroom poisoning (MP) can lead to various health issues, including severe liver or kidney failure, cardiac injuries, and neurological symptoms like delirium and seizures.
- A case study of a 68-year-old woman demonstrated severe cardiac arrhythmias and long QT syndrome following her mushroom exposure, although her kidney and liver functions remained normal.
- This case highlights the need for careful monitoring of cardiac function in MP patients, as toxic mushrooms can also affect the heart, necessitating further research into the underlying mechanisms.
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