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| http://dx.doi.org/10.1128/JCM.00381-13 | DOI Listing |
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Patient-derived response estimates from zero-passage organoids of luminal breast cancer.
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Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22908, USA.
Background: Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast cancer organoids are thought to retain tumor characteristics better, but long-term viability of luminal-subtype cases is a persistent challenge. Our goal was to adapt short-term organoids of luminal breast cancer for parallel testing of genetic and pharmacologic perturbations.
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State Key Laboratory Incubation Base for Conservation and Utilization of Bio-Resource in Tarim Basin, Alar, Xinjiang Uygur Autonomous Region, 843300, China.
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View Article and Find Full Text PDFMagnetic Carbon Bead-Based Concentration Method for SARS-CoV-2 Detection in Wastewater.
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Interdisciplinary Center for River Basin Environment, University of Yamanashi, 4-3-11 Takeda, Kofu, Yamanashi, 400-8511, Japan.
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View Article and Find Full Text PDFEnvironmental microbial reservoir influences the bacterial communities associated with Hydra oligactis.
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MTA-DE "Momentum" Ecology, Evolution & Developmental Biology Research Group, Dept. of Evolutionary Zoology, University of Debrecen, Debrecen, Hungary.
The objective to study the influence of microbiome on host fitness is frequently constrained by spatial and temporal variability of microbial communities. In particular, the environment serves as a dynamic reservoir of microbes that provides potential colonizers for animal microbiomes. In this study, we analyzed the microbiome of Hydra oligactis and corresponding water samples from 15 Hungarian lakes to reveal the contribution of environmental microbiota on host microbiome.
View Article and Find Full Text PDFCirculating Pre-microRNA-488 in Blood Is a Potential Prognostic Biomarker in Gastric Cancer.
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Department of Surgery, Kyushu University Beppu Hospital, Oita, Japan;
Background/aim: MicroRNAs (miRNAs) have been highlighted as non-invasive clinical biomarkers in liquid biopsy. This study aimed to investigate the clinical significance of circulating tumor suppressors, precursor-miR-488 (pre-miR-488) and miR-488-5p, in the blood of patients with gastric cancer (GC).
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