Deep-vein thrombosis (DVT) in children is most often secondary to a predisposing cause. DVT and septic pulmonary emboli in staphylococcal sepsis has been described most often with methicillin-resistant Staphylococcus aureus. The clinical features of four previously healthy children with community-acquired, methicillin-sensitive Staphylococcus aureus sepsis associated with DVT are described.
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