This study was carried out to determine the effects of methanolic extracts of L. on compared with Niclosomide. In this experimental study in September 2010, a number of leeches (70 in total) from the southern area of Ilam province were prepared, and the effects of methanolic extract of L. with Niclosomide as the control drug were compared and distilled water was evaluated as the placebo group which investigated using anti-leech assay. The average time of paralysis and death of for Niclosomide (1,250 mg/kg) and the methanol extract of L. (600 μg/ml) were 6.22 ± 2.94 and 68.44 ± 28.39 min, respectively. Distilled water and garlic tablets at a dose of 400 mg were determined as the inert group. In this research, the attraction time of the leeches' death among different treatments is significant. In this study, it was determined that Niclosomide, with an intensity of 4+, and methanolic extracts of L., with an intensity of 3+, have a good anti-leech effect and can be shown to be effective in cases of leech biting, while distilled water was negative.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590416PMC
http://dx.doi.org/10.1007/s00580-011-1380-7DOI Listing

Publication Analysis

Top Keywords

distilled water
12
compared niclosomide
8
effects methanolic
8
methanolic extracts
8
niclosomide
5
anti-immature leech
4
leech activity
4
activity compared
4
niclosomide study
4
study carried
4

Similar Publications

Ashwagandha (Withania somnifera), enriched in alkaloids, steroidal lactones and saponins, is a valuable herb in Indian Ayurvedic medicine. During December 2023, Va-1 (Vallabh Ashwagandha-1) plants at ICAR -Central Tobacco Research Institute, Vedasandur, Tamil Nadu (10.53717ºN, 77.

View Article and Find Full Text PDF

'Lanjingling' [China National Plant Variety Protection (CNPVP) 20200389] is the first new nationally registered cultivar of blue honeysuckle (Lonicera caerulea L.) developed by the Northeast Agricultural University for the fresh-fruit market (Zhu et al. 2022).

View Article and Find Full Text PDF

Intoxication of sheep and cattle by recently occurred in Uruguay and Argentina in association with severe drought. Although the disease was experimentally reproduced in sheep in the 1970s, there is limited information on clinical and pathologic findings of sheep experimentally intoxicated by this beetle. Here, we described the clinical, gross, and microscopic findings in 3 sheep orally dosed with (treatment group, TG) and in 2 control sheep (control group, CG) dosed with distilled water.

View Article and Find Full Text PDF

Puerarin Attenuates Podocyte Damage in Mice With Diabetic Kidney Disease by Modulating the AMPK/Nrf2 Pathway.

Int J Endocrinol

January 2025

Nephrology Department, Jiangxi Provincial Key Research Laboratory of Traditional Chinese Medicine, Key Research Laboratory of Chronic Renal Failure, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, China.

This study aimed to investigate the potential mechanisms of puerarin in alleviating diabetic nephropathy (DKD) in mice. The DKD model was induced by multiple low-dose injections of streptozotocin (STZ) and a high-sugar and high-fat diet in male C57BL/6J mice. After confirming the onset of DKD, mice were given irbesartan, distilled water, or different concentrations of puerarin (40 and 80 mg/kg/d) by gavage for 8 weeks.

View Article and Find Full Text PDF

The purpose of this trial was to assess the effects of methylphenidate on the kidney tissues and to investigate the protective effect of adenosine triphosphate (ATP) against possible methylphenidate nephrotoxicity in rats. The rats were separated into; healthy control (HG), methylphenidate (MPHG), ATP (ATPG), and ATP+ methylphenidate (AMPG). The ATPG and AMPG groups were administered ATP 4 mg/kg bw/d, and the HG and MPHG groups received distilled water intraperitoneally.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!