Background: G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation.
Methods: This study was performed on favism patients and healthy controls referring to Iranshahr central hospital. Liver and kidney function tests were performed.
Results: The results showed a statistically significant difference between these two groups (p <0.05) for liver function tests, (AST, ALT and ALP), but not for renal tests (BUN and creatinine) (p >0.05).
Conclusion: Due to abnormalities were seen in the liver function tests of these patients, we suggest that these tests be regularly performed for favism patients who are constantly exposed to oxidant agents.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592938 | PMC |
Patient Educ Couns
February 2025
Department of Paediatrics, Muscat Private Hospital, Muscat, Oman.
Genes (Basel)
October 2024
Departmental Unit of Molecular and Genomic Diagnostics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Genes (Basel)
August 2024
Internal Medicine Unit, Maggiore della Carità Hospital, 28100 Novara, Italy.
Consumption of fava beans in a patient with glucose-6-phosphate dehydrogenase (G6PD) deficiency, also called favism, can lead to a haemolytic crisis. We report the case of a 69-year-old patient of Iranian origin admitted to the emergency department following syncope. The patient's comprehensive interview and blood analysis revealed that the patient presented a haemolytic crisis triggered by fava beans consumption, due to previously undiagnosed G6PD deficiency.
View Article and Find Full Text PDFFront Microbiol
June 2023
Biotech@ISM, Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, Rome, Italy.
Introduction: Red blood cells (RBCs) are among the simplest, yet physiologically relevant biological specimens, due to their peculiarities, such as their lack of nucleus and simplified metabolism. Indeed, erythrocytes can be seen as biochemical machines, capable of performing a limited number of metabolic pathways. Along the aging path, the cells' characteristics change as they accumulate oxidative and non-oxidative damages, and their structural and functional properties degrade.
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