AI Article Synopsis
- Some ischemic stroke patients may experience hemorrhagic transformation, resulting in higher rates of health complications and death.
- The identification of biomarkers for ischemic strokes at risk for this transformation is crucial for potential changes in treatment strategies.
- This text reviews a trial that explored tight junction proteins as indicators of blood-brain barrier disruption and hemorrhagic transformation in ischemic stroke for the first time.
Article Abstract
Some patients with ischemic stroke are subject to hemorrhagic transformation, a complication leading to increased patient morbidity and mortality. The discovery of biomarkers that can be used to identify ischemic strokes prone to this complication are very important for the clinical practice because therapy could be altered to mitigate the risk. We discuss here the results of a trial that evaluated for the first time tight junction proteins as biomarkers of blood-brain barrier disruption and hemorrhagic transformation in ischemic stroke.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593289 | PMC |
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