AI Article Synopsis

  • Resistant hypertension is a persistent problem that modern medicine is still trying to tackle, prompting research into new treatment technologies.
  • Dysfunction of the sympathetic nervous system plays a key role in advancing hypertension, leading to clinical trials that show catheter-based renal denervation therapy as a safe and effective treatment option.
  • The review covers current knowledge about renal denervation therapy, its methods, limitations of existing data, and possible new targets for future treatment options.

Article Abstract

Resistant hypertension remains a challenging issue even for modern medicine. Therefore, research is focusing on the development of new technologies to optimize the treatment of this condition. It has been demonstrated that the dysfunction of the sympathetic nervous system is crucial in the development and maintenance of advanced stages of hypertension. Based on these findings, clinical trials have recently shown that catheter-based percutaneous renal denervation therapy is safe and effective in the treatment of resistant hypertension. This review discusses the current scientific knowledge of renal denervation therapy in resistant hypertension, including the different methods that have been described in the literature so far, as well as limitations of the available data. Furthermore, new potential targets for this fascinating therapy will be addressed.

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Source
http://dx.doi.org/10.1586/erd.13.1DOI Listing

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