A new synthesis of di- and trisubstituted pyrroles was achieved by treating in situ generated vinylogous diazoesters and readily available nitriles with a catalytic amount of silver(I) antimony hexafluoride at room temperature. This method showcased the potential of utilizing silver(I) carbenoids in preparing heterocyclic compounds.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol400062w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis of nonaromatic [16]thiatriphyrin(2.2.1)s.
Org Biomol Chem
January 2025
Department of Chemistry, IIT Bombay, Powai, Mumbai 400076, India.
[16]Thiatriphyrin(2.2.1)s containing one thiophene and two pyrroles connected five -carbons were synthesized by condensing a new precursor, -fused thiatripyrrane, with an appropriate aryl aldehyde in CHCl under acid-catalyzed inert conditions followed by open air oxidation with DDQ.
View Article and Find Full Text PDFBrCYP71 mutation resulted in stay-green in pak choi (Brassica rapa L. ssp. chinensis).
Theor Appl Genet
January 2025
College of Horticulture, Shenyang Agricultural University, Shenyang, 110866, People's Republic of China.
BrCYP71 encoding multifunctional oxidase was mapped using BSA-Seq and linkage analysis, and its function in stay-green of pak choi was verified through Arabidopsis heterologous transgenic experiment. Stay-green refers to the phenomenon that plant leaves remain green during senescence and even after death, which is of great significance for improving the commerciality of leafy vegetables during storage or transportation and extending their shelf life. In this study, we identified a stay-green mutant of pak choi and named it nye2.
View Article and Find Full Text PDFMolecular docking and differential rbcl gene expression reveal variation in glyphosate herbicide tolerance of sugarcane varieties.
Mol Biol Rep
January 2025
Agricultural Research Center(ARC), Sugar Crops Research Institute(SCRI), Giza, Egypt.
Background: Glyphosate is an extensively employed herbicide in agriculture, specifically for sugarcane cultivation. The situation is different with the extensive physiological and genetic effects exerted by this herbicide on a range of plant species, including sugarcane, whose model basis is still poorly characterized, although its primary mode of action, which acts on the EPSPS enzyme in the shikimic acid pathway, is completely elucidated. The current study was aimed at investigating the stability of glyphosate formulation, molecular interactions of glyphosate formulation with rbcL enzyme associated with chlorophyll metabolism, and its effects on varieties of sugarcane.
View Article and Find Full Text PDFHeme oxygenase, biliverdin reductase, and bilirubin pathways regulate oxidative stress and insulin resistance: a focus on diabetes and therapeutics.
Clin Sci (Lond)
January 2025
Drug & Disease Discovery D3 Research Center, Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, USA.
Metabolic and insulin-resistant diseases, such as type 2 diabetes mellitus (T2DM), have become major health issues worldwide. The prevalence of insulin resistance in the general population ranges from 15.5% to 44.
View Article and Find Full Text PDFInvestigation into the effect of phenylalanine gating on anaerobic haem breakdown using the energy landscape approach.
Protein Sci
February 2025
Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
We have recently demonstrated a novel anaerobic NADH-dependent haem breakdown reaction, which is carried out by a range of haemoproteins. The Yersinia enterocolitica protein, HemS, is the focus of further research presented in the current paper. Using conventional experimental methods, bioinformatics, and energy landscape theory (ELT), we provide new insight into the mechanism of the novel breakdown process.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!