Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case.

Case Rep Pediatr

Pediatric Congenital Hematologic Disorders Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Published: March 2013

Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and a leading cause of acquired heart disease. It is assumed that there is an activation of the immune system by an infectious trigger in a genetically susceptible host. Neuroblastoma is the most common extracranial solid tumor in young children. It mainly originates from primordial neural crest cells that generate the adrenal medulla and sympathetic ganglia. A diagnosis of concurrent KD and neuroblastoma in a living child has been made in only one previous report. We report the second case and review the literature.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580901PMC
http://dx.doi.org/10.1155/2013/931703DOI Listing

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