AI Article Synopsis

  • The study focused on the use of intraperitoneal chemotherapy for post-surgical treatment of ovarian cancer, involving 24 patients.
  • Among those with bulky disease, results showed a high complication rate and poor therapeutic outcomes.
  • However, patients with microscopic disease and residual tumors smaller than 2 cm appeared to benefit from the treatment, despite Mitoxantrone causing local discomfort and potential peritonitis.

Article Abstract

The Authors report their experience with intraperitoneal chemotherapy in post surgical management of ovarian cancer. 24 patients were evaluable for the study and the results indicate that in patients with bulky disease the complication rate was high and the therapeutical outcome very poor. Only in patients with microscopic disease and residual tumor smaller than 2 cm seemed to benefit from intraperitoneal chemotherapy. Despite pharmacological advantages, Mitoxantrone causes local discomfort up to peritonitis.

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