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Seasonal variations and environmental influences on dry eye operations in Japan.
Sci Rep
December 2024
Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan.
The surface of the eye is constantly exposed to the external environment and is affected by atmospheric conditions and air pollution, and dry eye is a typical ocular surface disease. The aim of this study is to determine whether there are seasonal differences in the number of dry eye operations in Japan and to investigate whether meteorological conditions and air pollutants are related to. The operations were examined using the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) database from fiscal years 2019 to 2021.
View Article and Find Full Text PDFEmerging Role of Gut Microbiota in Breast Cancer Development and Its Implications in Treatment.
Metabolites
December 2024
Mubarak Hospital, Srinagar 190002, Jammu and Kashmir, India.
The human digestive system contains approximately 100 trillion bacteria. The gut microbiota is an emerging field of research that is associated with specific biological processes in many diseases, including cardiovascular disease, obesity, diabetes, brain disease, rheumatoid arthritis, and cancer. Emerging evidence indicates that the gut microbiota affects the response to anticancer therapies by modulating the host immune system.
View Article and Find Full Text PDFBayesian Latent Class Models for Evaluating the Validity of Claim-based Definitions of Disease Outcomes.
Ann Clin Epidemiol
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Center of Medical Statistics, Minato-Ku, Tokyo, Japan.
Background: Large electronic databases have been widely used in recent years; however, they can be susceptible to bias due to incomplete information. To address this, validation studies have been conducted to assess the accuracy of disease diagnoses defined in databases. However, such studies may be constrained by potential misclassification in references and the interdependence between diagnoses from the same data source.
View Article and Find Full Text PDFImpact of sending vouchers for a community-based oral screening program on dental service usage promotion among adults: a difference-in-difference analysis.
BMC Health Serv Res
December 2024
Health Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.
Background: Community- and evidence-based approaches are essential for improving dental public health. We evaluated the effectiveness of sending vouchers in a community-based oral screening program to encourage dental visits and improve oral health among adults.
Methods: We analyzed the data from April 2014 to March 2019 obtained from administrative claims and screening program databases in Tsukuba City, Japan.
Tortured confessions? Potentially erroneous statistical inferences may underpin misleading claims of harms in reanalyses of COVID-19 and HPV vaccines.
Vaccine
December 2024
TCD Biostatistics Unit, Discipline of Public Health and Primary Care, School of Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:
The safety and efficacy of vaccination is a subject contentious in the public mind. Despite overwhelming evidence of their benefits to public health, COVID-19 and human papilloma virus (HPV) vaccines have been the focus of intense concerns. While the original phase III trials and post-market phase IV studies have continued to show their benefits and positive safety profile, some authors have attempted to reassess the original trial data, purporting to showing hidden harms for both COVID-19 and HPV vaccines.
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