Birth defects after incestuous mating: calculating the probability of causality and reflecting on the desirability of genetic testing.

Eur J Med Genet

Department of Clinical Genetics and Institute of Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

Published: May 2013

In this short communication we (1) show that, despite the rarity of autosomal recessive inheritance, primary congenital hydrocephalus in a girl stemming from father-daughter incest is most likely due to the incestuous union of her parents, and (2) reflect on the question, among others, whether actual genetic work-up to support victim indemnification is ever in the interest of the child.

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Source
http://dx.doi.org/10.1016/j.ejmg.2013.02.007DOI Listing

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