We have developed a new finite element (FE) model of human right ear, including the accurate geometry of middle ear ossicles, external ear canal, tympanic cavity, and mastoid cavity. The FE model would be suitable to study the dynamic behaviors of pathological middle ear conditions, including changes of stapedial ligament stiffness, tensor tympani ligament (TTL), and tympanic membrane (TM) stiffness and thickness. Increasing stiffness of stapedial ligament has substantial effect on stapes footplate movement, especially at low frequencies, but less effect on umbo movement. Softer TTL will result in increasing umbo and stapes footplate displacement, especially at low frequencies (f<1000Hz). When the TTL was detached, the vibration amplitude of umbo increased by 6dB at 600Hz and two peaks (300 and 600Hz) were found in the vibration amplitude of stapes footplate. Increasing the stiffness of tensor tympani resulted in a slightly decreased umbo amplitude at very low frequencies (f<500Hz) and significantly decreased displacement up to 12dB at middle frequencies (1000Hz
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http://dx.doi.org/10.1016/j.kjms.2012.08.023 | DOI Listing |
Laryngoscope Investig Otolaryngol
February 2025
Objective: The primary aim of this study was to investigate the accuracy of a semi-automatic algorithm in assessing the feasibility and complexity of endoscopic stapes surgery preoperatively.
Methods: A semi-automatic algorithm was developed to simulate endoscopic stapes surgery in 3D. To test the accuracy of the algorithm, five fresh-frozen cadaveric heads (ten ears) were used.
OTO Open
January 2025
Lebanese Otolaryngology Research and Awareness Group (LORAG) Beirut Lebanon.
Objective: This study aims to compare research productivity and barriers to research between high-income countries (HICs) and low- and middle-income countries (LMICs) otolaryngologists.
Study Design: Cross-sectional survey.
Setting: International survey.
Nat Commun
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Study Center for Ocular Diseases, Guangzhou, China.
Photoreceptors are specialized neurons at the core of the retina's functionality, with optical accessibility and exceptional sensitivity to systemic metabolic stresses. Here we show the ability of risk-free, in vivo photoreceptor assessment as a window into systemic health and identify shared metabolic underpinnings of photoreceptor degeneration and multisystem health outcomes. A thinner photoreceptor layer thickness is significantly associated with an increased risk of future mortality and 13 multisystem diseases, while systematic analyses of circulating metabolomics enable the identification of 109 photoreceptor-related metabolites, which in turn elevate or reduce the risk of these health outcomes.
View Article and Find Full Text PDFJ Small Anim Pract
January 2025
Surgical Unit, Centre Hospitalier Vétérinaire St Martin, Allonzier La Caille, France.
Objectives: To report the compartmental location of feline aural inflammatory polyps within the tympanic bulla.
Materials And Methods: Nine client-owned cats with clinical signs and middle ear filling consistent with feline aural inflammatory polyps were prospectively pre-selected and underwent unilateral or bilateral ventral bulla osteotomy. Preoperative and surgical findings, complications and outcomes were recorded.
J Clin Endocrinol Metab
January 2025
Division of Orthogenetics, Department of Pediatrics, Nemours Children's Hospital, Delaware, 1600 Rockland Road, Wilmington, DE, 19803, USA.
Achondroplasia is the most common disproportionate short-stature skeletal dysplasia. Features associated with achondroplasia are rhizomelia, macrocephaly, midface hypoplasia, and typical cognition. Potential medical complications include foramen magnum stenosis, hydrocephalus, middle ear dysfunction, obstructive and central sleep apnea, spinal stenosis and genu varum.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!