Background: Although many Asian atopic patients have orbital darkening symptom and the demand to treat this condition is increasing, little has been reported in the literature on the treatment of infraorbital dark circles in atopic dermatitis.
Objective: To evaluate the clinical efficacy and safety of 2790-nm erbium:yttrium scandium gallium garnet (Er:YSGG) laser therapy for reducing infraorbital dark circles in atopic dermatitis patients.
Materials And Methods: Ten Korean patients over 21 year with mild atopic dermatitis and infraorbital dark circles were enrolled in this study. Patients who need active atopic dermatitis treatments are excluded because of the possibility of aggravation after laser treatment. They were treated for dark circles using a 2790-nm Er:YSGG laser. The treatment parameters were 1.8-2.2 J/cm² fluence, 6-mm spot size, and 0.3-ms pulse width with 10% overlap over the infraorbital areas once with a 4-week interval between treatments. Efficacy was assessed with a quartile grading score ranging from 0 to 5 by a blinded investigator, and the patients also documented their degree of satisfaction with the same grading score. All possible side effects were evaluated.
Results: The clinical assessment showed 74.5% (2.7) and 72.5% (2.5) improvements, and the patient satisfaction scale scores improved an average of 74% (2.4) and 71.5% (2.3) at 2 months and 4 months after treatment, respectively. There were no severe side effects or aggravation of atopic dermatitis.
Conclusion: Our study suggests that 2790-nm Er:YSGG laser therapy can be effectively and safely used in the treatment of infraorbital dark circles in atopic dermatitis patients.
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http://dx.doi.org/10.3109/14764172.2012.759236 | DOI Listing |
Int J Cosmet Sci
January 2025
Genomic Sciences and Biotechnology Program, Catholic University of Brasilia, Brasília, Federal District, Brazil.
Background: The aging of the skin, particularly around the periorbital region, is a complex process characterized by the accumulation of senescent cells, decreased collagen production, and reduced skin elasticity, leading to visible signs such as fine lines, wrinkles, and sagging.
Objective: This study investigates the efficacy of a novel topical formulation, OS-01 EYE, containing the senomorphic peptide, OS-01, along with other active ingredients, in improving the skin around the eyes.
Methods: A 12-week clinical study was conducted with 22 participants who applied OS-01 EYE twice daily.
Introduction: Periorbital melanosis (POM) is a poorly defined condition that is becoming an increasing aesthetic concern. With its multifactorial origin, it necessitates a thorough assessment of targeted multimodal treatments. The psychological impact and underlying pathogenesis have been underexplored, as evidenced by the gap between the roughly 100 indexed articles and the 150 million search engine results on treatments for dark circles.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
November 2024
Pak Emirates Military Hospital, Rawalpindi-Pakistan.
J Craniofac Surg
November 2024
Department of Plastic Surgery, Armed Forces Capital Hospital, Bundang-gu, Seongnam, Gyeonggi-do.
In this paper, the authors aim to explore the reasons behind human makeup from both medical and literary perspectives. In a PubMed search for "makeup and cosmetics," 509 titles were identified. Of these, 64 abstracts were reviewed, and ultimately, 8 full texts were referenced.
View Article and Find Full Text PDFAesthetic Plast Surg
November 2024
Department of Plastic and Reconstructive Surgery, Shanghai 9thPeople's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Tissue Engineering, National Tissue Engineering Center of China, 639 ZhiZaoJu Road, Shanghai, 200011, China.
Background: The formation of infraorbital dark circles involves various factors including hyperpigmentation, skin aging and laxity. This study is to investigate whether cell-free fat extract (CEFFE) inhibits melanin synthesis and improves the appearance of infraorbital dark circles.
Methods: Imaging systems analysed the melanin content in three groups of zebrafish embryos treated with 0 (CTRL), 100, and 200μg/mL of CEFFE.
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