10 patients have been treated by subcutaneous injections of placebo three times weekly for 4 weeks within a phase-I trial of BCH-069. Immunological, hematological and biochemical parameters were observed at different times: preseasonal, seasonal and postseasonal. --Some new observations are reported, which are induced by the seasonal inflammation. For example there was a strong increase of C-reactive protein and also an increase in the triglyceride level. --The parameters could be useful for trials of new antiallergic drugs in hay fever in the future.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[disease-specific non-specific
4
non-specific seasonal
4
seasonal parameter
4
parameter changes
4
changes hayfever
4
hayfever patients]
4
patients] patients
4
patients treated
4
treated subcutaneous
4
subcutaneous injections
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!