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Physician assistant/associate career flexibility: factors associated with specialty transitions.
BMC Health Serv Res
December 2024
National Commission on Certification of Physician Assistants, 12000 Findley Road, Suite 200, Johns Creek, Georgia, 30097, USA.
Background: Physician assistants/associates (PAs), due to their broad medical education and certification, have the flexibility to change specialties throughout their careers. Prior studies suggest that between half and three-quarters exercise this option at some point in their career, and a third do so within the first decade. However, more research is needed to understand the factors associated with PAs changing vs.
View Article and Find Full Text PDFFrom intensive care monitors to cloud environments: a structured data pipeline for advanced clinical decision support.
EBioMedicine
December 2024
Department of Anaesthesiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Background: Clinical decision-making is increasingly shifting towards data-driven approaches and requires large databases to develop state-of-the-art algorithms for diagnosing, detecting and predicting diseases. The intensive care unit (ICU), a data-rich setting, faces challenges with high-frequency, unstructured monitor data. Here, we showcase a successful example of a data pipeline to efficiently move patient data to the cloud environment for structured storage.
View Article and Find Full Text PDFAdsorption and Sensing Performance of Transition Metal Decorated Graphene Quantum Dots for AsH, NH, PH, and HS.
Langmuir
December 2024
Department of Physics, National Institute of Technology, Jamshedpur-831014, India.
We have conducted a systematic study employing density functional theory (DFT) and quantum theory of atoms in molecules (QTAIM) to explore the gas sensing capabilities of nitrogen-doped single vacancy graphene quantum dots (SV/3N) decorated with transition metals (TM = Mn, Co, Cu). We have studied the interactions between TM@SV/3N and four different target gases (AsH, NH, PH, and HS) through the computation of adsorption energies, charge transfer, noncovalent interaction, density of states, band gap, and work function for 12 distinct adsorption systems. Our comprehensive analysis included an in-depth assessment of sensors' stability, sensitivity, selectivity, and reusability for practical applications.
View Article and Find Full Text PDFCorrection method of Mohr-Coulomb strength criterion for rock based on freeze-thaw and residual effects.
Sci Rep
December 2024
Department of Mechanics, Xi'an University of Science and Technology, Xi'an, 710054, China.
Under confining pressure, rocks transition from brittle failure to plastic failure, and residual strength exists after complete failure. However, in the process of establishing rock damage constitutive models, the strength criteria used usually do not consider residual stress. In cold region engineering, the freeze-thaw effect caused by temperature changes should be considered in the constitutive model, and strength criteria should also be introduced.
View Article and Find Full Text PDFEPLIN, a prospective oncogenic molecule with contribution to growth, migration and drug resistance in pancreatic cancer.
Sci Rep
December 2024
School of Medicine, Cardiff University, Henry Wellcome Building, Cardiff, CF14 4XN, UK.
Most pancreatic cancer patients are diagnosed at advanced stages, with poor survival rates and drug resistance making pancreatic cancer one of the highest causes of cancer death in the UK. Understanding the underlying mechanism behind its carcinogenesis, metastasis and drug resistance has become an essential task for researchers. We have discovered that a well-established tumour suppressor, EPLIN, has an oncogenic rather than suppressive role in pancreatic cancer.
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