A sensitive method based on programmable temperature vaporization large volume injection coupled to gas chromatogram and high-resolution mass spectrometry (PTV-GC-HRMS) has been developed for the determination of ultra trace levels of dioxin-like polychlorinated biphenyls (DL PCBs) in small amounts of human blood. Blood samples (1mL) were first extracted by column extraction and then purified with column chromatorgraphies. Final extracts (20μL) were introduced to the PTV injector under the solvent vent mode and detected by GC-HRMS (SIM mode). PTV parameters were observed by changing one factor at a time (practical conditions: vent flow: 50mLmin(-1), vent pressure: 0kPa and vent time: 0.1min), recoveries of most PCB congeners ranged from 55.1% to 108%, and method detection limits were in the range of 0.11-1.63pgg(-1).
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Prioritising relevant polychlorinated naphthalene (PCN) congeners for human dietary exposure studies.
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Bursa Technical University, Department of Environmental Engineering, Bursa, Türkiye. Electronic address:
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Article Synopsis
- The study reveals that even though the use of polychlorinated naphthalenes (PCNs) was banned long ago, they are still found in South Korean soils due to their persistence and emissions from industrial activities.
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Association between mixed exposure to dioxins and dioxin-like polychlorinated biphenyls and obesity among U.S. adults.
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