AI Article Synopsis
- Ischemia reperfusion is a crucial process during transplantation that leads to injuries in the graft, causing early and potentially chronic dysfunction.
- These injuries result from specific pathophysiological changes that compromise the overall success of the graft.
- Advances in immunosuppressive drug regimens highlight the importance of managing ischemia reperfusion injury to develop new therapeutic strategies that enhance graft quality and function.
Article Abstract
During the transplantation procedure, ischemia reperfusion is an inevitable situation characterized by specific pathophysiological processes, which ultimately act synergistically to create injuries in the graft. These injuries are involved in early graft dysfunctions which promote chronic dysfunction and compromise graft outcome. Progresses in immunosuppressive drug regimens now place ischemia reperfusion injury control at the forefont for innovative therapeutic strategy to improve the quality of the graft. This review details these different processes and its consequences on renal graft function underlying the interest of novel therapeutic strategy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1051/medsci/2013292016 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!