In a recent issue of Neuron, Chen et al. (2013) show that apoptosis is required to ensure the even distribution of a class of retinal ganglion cells (ipRGCs), which sense luminance both intrinsically and through input from rods and cones. Disrupting apoptosis impairs photoentrainment mediated by rods/cones, but not that mediated by ipRGC-expressed melanopsin.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744582 | PMC |
http://dx.doi.org/10.1016/j.devcel.2013.02.001 | DOI Listing |
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