Dying to entrain: regulating ipRGC spacing.

Dev Cell

Center for Developmental Genetics, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA.

Published: February 2013

In a recent issue of Neuron, Chen et al. (2013) show that apoptosis is required to ensure the even distribution of a class of retinal ganglion cells (ipRGCs), which sense luminance both intrinsically and through input from rods and cones. Disrupting apoptosis impairs photoentrainment mediated by rods/cones, but not that mediated by ipRGC-expressed melanopsin.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744582PMC
http://dx.doi.org/10.1016/j.devcel.2013.02.001DOI Listing

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