Acute high altitude disease(AHAD), which can be divided into acute mountain disease (AMS), high altitude pulmonary edema (HAPE) and high altitude cerebral edema (HACE), is one of the special illnesses occurred at high altitude, commonly encountered by travelers to high altitudes (>2 500 m), which affects people's work capacity and health and could be even a life-threatening disease. Despite extensive investigations over the last century, the pathophysiology of AHAD remains elusive. Nevertheless, numerous researches have confirmed the existence of AHAD susceptibility differences. The aim of this paper was to review the epidemiological evidence for a genetic component to the various forms of AHAD so far, as well as to supply helpful reference to its epidemiological studies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3724/sp.j.1005.2013.00141 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Indoor air quality and human health risk assessment in selected high-altitude villages of Gilgit-Baltistan, Pakistan.
Environ Monit Assess
January 2025
Department of Environmental Sciences, Karakoram International University, Gilgit, Gilgit-Baltistan, Pakistan.
This research marks the inaugural endeavor in Gilgit-Baltistan (GB) to identify the primary sources of household energy and indoor air pollutants (IAPs) during the winter and additionally, to evaluate the health impacts associated with IAPs within specific high-altitude communities in Gilgit-Baltistan, Pakistan. Using the convenience sampling method, 20 households were continuously monitored to assess IAPs based on standards time-weighted average. The study found that 90% of the population relied primarily on animal dung as their main energy source, with wood, agricultural residues, electricity, and gas as other sources.
View Article and Find Full Text PDFMolecular Phylogeny and Morphology Reveal Four New Species of (Bolbitiaceae, Agaricales) from the Qinghai-Xizang Plateau, China.
J Fungi (Basel)
January 2025
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
The Qinghai-Xizang Plateau, known for its high altitude, geological history of plate collision, crustal uplift, and special ecology factors, provides an ideal environment for studying fungal biodiversity in extreme environmental conditions. Some species within the , containing secondary metabolites such as psilocybin, phallotoxins, and amatoxins, have potential medicinal value for treating psychiatric disorders and for use in drug development. This study investigates (Bolbitiaceae, Agaricales) on the Plateau, based on specimens collected over the past decade, using morphological and molecular phylogenetic analyses.
View Article and Find Full Text PDFAnti-arthritic Effects of Undifferentiated and Chondrogenic Differentiated MSCs in MIA-induced Osteoarthritis in Wistar Rats: Involvement of Oxidative Stress and Immune Modulation.
Curr Stem Cell Res Ther
January 2025
Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P.O. Box 62521, Beni-Suef, Egypt.
Introduction: Osteoarthritis (OA) is a degenerative joint disease that can affect the many tissues of the joint. There are no officially recognized disease-modifying therapies for clinical use at this time probably due to a lack of complete comprehension of the pathogenesis of the disease. In recent years, emerging regenerative therapy and treatments with stem cells both undifferentiated and differentiated cells have gained much attention as they can efficiently promote tissue repair and regeneration.
View Article and Find Full Text PDFSynthesis of chiral mesoporous silica nanoparticles for the adsorptive removal of the chiral insecticide sulfoxaflor from water.
Nanoscale Adv
December 2024
Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University Taif 21944 Saudi Arabia.
Mesoporous materials have garnered significant interest because of their porous structure, large surface area and ease of surface functionalization to incorporate the functional groups of choice. Herein, chiral mesoporous silica nanoparticles (CMSNPs) were prepared using quaternary amino silane as the template, tetramethyl orthosilicate as the silica source and proline and cellulose as chiral selector. The developed CMSNPs were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), elemental analysis, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction analysis, BET surface area analysis and BJH pore size/volume analysis.
View Article and Find Full Text PDFImpact of high hemoglobin levels on carotid artery intima-media thickness and its predictive value for hypertension in high-altitude areas: a real-world study.
Front Cardiovasc Med
January 2025
Hyperbaric Oxygen, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Background And Purpose: The hemoglobin levels in the peripheral blood of individuals living at high altitudes are significantly higher than normal levels. These levels are closely associated with atherosclerosis and cardiovascular events. This study aimed to investigate the correlation between hemoglobin levels in the peripheral blood and hypertension in high-altitude regions, providing a basis for preventing and treating primary hypertension in these regions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!