An aqueous colloid dispersion of gold nanoparticles (AuNPs) was prepared by reduction of gold(III) chloride and its interaction with three local anesthetics (procaine, dibucaine or tetracaine) was investigated. Optical spectra reveal the modifications in the absorption band of nanoparticles related to their self assembly mediated by anesthetic molecules and depending on the progress in time of the aggregation process. TEM images show the features of the self assemblies formed by the association of gold nanoparticles in presence of anesthetics, and reveal marked differences in the behavior of the AuNPs against the three anesthetics. The main effect of various anesthetics can be described in terms of electrostatic forces between the negatively charged metal nanoparticles and anesthetic molecules, existing in their cationic form at the working pH. Then, the anesthetics functionalized nanoparticles trigger specific interactions to form different self assemblies through a selective combination of hydrophobic and hydrogen bonding interactions between the coated nanoparticles and anesthetics molecular species.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1166/jnn.2012.6707 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
PtAu-Carbon Nanotube/Glassy Carbon Electrode Composite based Electrochemical Sensor for High-Precision Detection of Tetracycline.
Chempluschem
January 2025
Jiangsu Agri-animal Husbandry Vocational College, Department of Pharmacy, CHINA.
With enrichment of tetracycline (TC) in ecosystems, its accurate detection has become a major concern. Noble-metal nano-particles have attracted great interest as potential materials for sensing applications because of their remarkable electrical properties and adaptability. Herein, a novel electro-chemical detection technique based on carbon nano-tubes (CNTs) as the support material is developed to detect TC with high precision.
View Article and Find Full Text PDFUltrasensitive point-of-care multiplex diagnosis for influenza virus based robust quantum dot microsphere-lateral flow immunoassay.
Biosens Bioelectron
January 2025
Key Lab for Special Functional Materials of Ministry of Education, and School of Nanoscience and Materials Engineering, Henan University, 475004, Kaifeng, China. Electronic address:
Influenza A virus (IAV) and influenza B virus (IBV) with similar symptoms of infection caused a serious disease burden and economic losses in annual epidemic season, so it is important to quickly and accurately detect and distinguish between IAV and IBV during influenza season. Herein, the quantum dot microspheres (QDMS) were synthesized and applied to lateral flow immunoassays (LFIA), and a point-of-care (POC) biosensor that can discriminately and simultaneously diagnose IAV and IBV within 10 min was established. A double-sandwich QDMS nanotags was synthesized by immobilizing hydrophobic quantum dots (QDs) with chemical bonding method on a silica sphere template with an outer silica shell protection showed excellent stability and high fluorescence.
View Article and Find Full Text PDFGreen synthesis of silica-coated gold nanoparticles employing femtosecond laser, solid targets, and water.
Discov Nano
January 2025
Nuclear and Energy Research Institute, IPEN, CNEN/SP, Av. Prof. Lineu Prestes, 2242, São Paulo, SP, CEP05508-000, Brazil.
Gold nanoparticles are widely used in biomedical applications due to their unique properties. However, traditional synthesis methods generate contaminants that cause cytotoxicity and compromise the biocompatibility of the nanomaterials. Therefore, green synthesis methods are essential to produce pure and biocompatible nanoparticles, ensuring their effectiveness in biomedical applications.
View Article and Find Full Text PDFDepolarized Forward Light Scattering for Subnanometer Precision in Biomolecular Layer Analysis on Gold Nanorods.
J Phys Chem Lett
January 2025
Department of Physics, Chalmers University of Technology, 412 96 Göteborg, Sweden.
Functional gold nanoparticles have emerged as a cornerstone in targeted drug delivery, imaging, and biosensing. Their stability, distribution, and overall performance in biological systems are largely determined by their interactions with molecules in biological fluids as well as the biomolecular layers they acquire in complex environments. However, real-time tracking of how biomolecules attach to colloidal nanoparticles, a critical aspect for optimizing nanoparticle function, has proven to be experimentally challenging.
View Article and Find Full Text PDFFlexible and Durable Conducting Fabric Electrodes for Next-Generation Wearable Supercapacitors.
ACS Appl Mater Interfaces
January 2025
Department of Physics, School of Electrical and Electronics Engineering, SASTRA Deemed to be University, Thanjavur 613 401, Tamil Nadu, India.
This study presents the fabrication of highly conducting Au fabric electrodes using a layer-by-layer (LBL) approach and its application toward energy storage. Through the ligand-exchange mechanism, the alternating layers of tris(2-aminoethyl)amine (TREN) and gold nanoparticles (Au NPs) encapsulated with tetraoctylammonium bromide (TOABr) ligands (Au-TOABr) were deposited onto the fabric to achieve a highly conducting Au fabric (0.12 Ω/□) at room temperature in just two LBL cycles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!