Doctors have a variety of drug options for treatment of depression. But there is currently no way to determine which antidepressant will work best for a given patient, which means that many people continue to suffer while their doctors try a series of medications. As Marisa Toups and Madhukar H. Trivedi write, however, many researchers have focused their efforts on developing biomarkers for depression-tests for aspects of a patient's physiology that can predict a clinical outcome. In the future, doctors may be able to screen patients to determine which treatment options will work for them, reducing the time a patient must continue to live with the effects of depression.
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Plant Foods Hum Nutr
December 2024
Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, 11000, Serbia.
Cellulite is an aesthetically distressing skin condition occurring in 80-90% of females and manifesting as dimples and depressions, producing an uneven surface to the skin. Our aim was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 32 days on cellulite reduction. Twenty women aged 21-49 with a cellulite grade of 1-2 according to the Nurnberger-Muller scale were participating in the study.
View Article and Find Full Text PDFDisabil Rehabil
December 2024
School of Medicine Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO, USA.
Purpose: To examine the effects of leisure participation on mental health for middle-aged and older adults with physical disabilities.
Materials And Methods: A systematic review conducted in March-May 2022 with an updated search in February 2024 retrieved data from MEDLINE, CINAHL, PsycInfo, and EMBASE. Inclusion criteria included a study population with a mean age ≥45 years and with physical disability, and original, peer-reviewed literature.
Nutr Rev
December 2024
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, United Kingdom.
Context: The use of prebiotics and probiotics as a treatment for psychiatric conditions has gained interest due to their potential to modulate the gut-brain axis. This review aims to assess the effectiveness of these interventions in reducing symptoms of depression and anxiety in psychiatric populations.
Objective: The aim was to comprehensively review and appraise the effectiveness of prebiotic, probiotic, and synbiotic interventions in reducing clinical depression and anxiety symptoms.
Psychol Health Med
December 2024
Play Therapy and Counseling, Sen Değilim Special Education and Rehabilitation Center, Istanbul, Turkiye.
Studies demonstrate that mothers of children with autism spectrum disorder (ASD) experience depression and are less likely to seek professional psychological help. This study examined the roles of coping strategies in predicting psychological help-seeking attitudes among mothers of children with ASD. A total of 250 Turkish mothers of children with autism were recruited using purposive sampling during their training at the autism center in Istanbul.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2024
Mental Health Research Centre, Moscow, Russia.
Objective: Identification of therapeutic targets in the treatment of adolescent depression with attenuated symptoms of schizophrenia and assessment of the effectiveness of therapeutic interventions.
Material And Methods: One hundred and twenty-three patients (mean age 19.6±2.
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