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The kidney reabsorption-related magnesium depletion score is associated with cardiovascular disease and longitudinal mortality in diabetic kidney disease patients.
Diabetol Metab Syndr
January 2025
Department of Urology, Ningbo Mingzhou Hospital, Zhejiang, China.
Background: The kidney reabsorption is essential for maintaining magnesium homeostasis. This study aims to explore the relationship between kidney reabsorption-related magnesium depletion score (MDS) and the occurrence of cardiovascular disease (CVD) and prognosis in diabetic disease kidney (DKD) patients.
Methods: We included 3199 DKD patients from the National Health and Nutrition Examination Survey (NHANES) database, including 1072 CVD patients.
Extracellular matrix stiffness regulates colorectal cancer progression via HSF4.
J Exp Clin Cancer Res
January 2025
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
Background: Colorectal cancer (CRC) has high incidence and mortality rates, with severe prognoses during invasion and metastasis stages. Despite advancements in diagnostic and therapeutic technologies, the impact of the tumour microenvironment, particularly extracellular matrix (ECM) stiffness, on CRC progression and metastasis is not fully understood.
Methods: This study included 107 CRC patients.
Health system financing fragmentation and maternal mortality transition in Mexico, 2000-2022.
Int J Equity Health
January 2025
Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Objective: To analyze the temporal and territorial relationship between health system financing fragmentation and maternal mortality in the last two decades in Mexico.
Methods: We conducted an ecological-longitudinal study of the maternal mortality ratio (MMR) in the 32 states of Mexico during the period 2000-2022. Annual MMRs were estimated at the national and state levels according to health insurance.
A quality improvement initiative aimed at reducing service strain and improving physician wellness in internal medicine.
BMC Med Educ
January 2025
Division of General Internal Medicine, Department of Medicine, The Ottawa Hospital, Ottawa, Canada.
Introduction: Hospital strain has been shown to negatively impact physician wellness, educational experience, and patient care. To address rising service demands, a non-academic hospitalist service was implemented to reduce daily clinical teaching unit (CTU) census by approximately 30%. Secondary aims were to evaluate physician and trainee wellness on CTU as well as assess unintended adverse patient outcomes.
View Article and Find Full Text PDFMortality in the families of children during the COVID-19 pandemic: evidence from a repeated cross-sectional study of children in the United States.
BMC Public Health
January 2025
Division of General Medicine, University of Michigan Medical School, Ann Arbor, USA.
Background: Modeling studies suggest that hundreds of thousands of U.S. children have lost caregivers since the COVID-19 pandemic began.
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